Peer Reviewed

1

Document Type

Article

Publication Date

26-8-2009

Keywords

Streptococci, bacteria, cardiovascular disease, oral pathogens, platelets, thrombosis, virulence.

Comments

The Version of Scholarly Record of this Article is published in Journal of Oral Microbiology. 2009 available online at: http://www.tandfonline.com/ DOI: 10.3402/jom.v1i0.1999

Abstract

In recent times the concept of infectious agents playing a role in cardiovascular disease has attracted much attention. Chronic oral disease such as periodontitis, provides a plausible route for entry of bacteria to the circulation. Upon entry to the circulation, the oral bacteria interact with platelets. It has been proposed that their ability to induce platelet aggregation and support platelet adhesion is a critical step in the pathogenesis of the infection process. Many published studies have demonstrated multiple mechanisms through which oral bacteria are able to bind to and activate platelets. This paper will review the various mechanisms oral bacteria use to interact with platelets.

Disciplines

Pharmacy and Pharmaceutical Sciences

Citation

Kerrigan SW, Cox D. The thrombotic potential of oral pathogens. Journal of Oral Microbiology. 2009;1.

PubMed ID

21523210

DOI Link

10.3402/jom.v1i0.1999

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 3.0 License

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