Most Recent Additions

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Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711.
Nyree Crawford, Manuela Salvucci, Christian T Hellwig, Frank A Lincoln, Ruth E Mooney, Carla L O'Connor, Jochen Hm Prehn, Daniel B Longley, and Markus Rehm

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Successful kidney transplantation normalizes platelet function
Claire Kennedy, Limy Wong, Donal J. Sexton, Jonathan Cowman, Irene Oglesby, Martin Kenny, Peter J. Conlon, and Dermot Kenny

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BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer
Sarah Shields, Emer Conroy, Tony O'Grady, Alo McGoldrick, Kate Connor, Mark P. Ward, Zivile Useckaite, Eugene Dempsey, Rebecca Reily, Youe Fan, Anthony Chubb, Gomez-Matallanas, Elaine W. Kay, Darran P O'Connor, Amanda McCann, William N. Gallagher, and Judith A. Coppinger

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Distinct moieties underlie biphasic H+ gating of connexin43 channels, producing a pH optimum for intercellular communication
Carolina D. Garciarena, Akif Malik, Pawel Swietach, Alonso P Moreno, and Richard D Vaughan-Jones

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An Audit of Neural Tube Defects in the Republic Of Ireland for 2012-2015.
Robert J. McDonnell, V Delany, M T. O'Mahony, Catherine Lynch, Aoife McKeating, Cathy Monteith, and Michael JA Turner

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Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment.
Sean Fitzgerald, Virginia Espina, Lance Liotta, Katherine M. Sheehan, Anthony O'Grady, Robert Cummins, Richard O'Kennedy, Elaine W. Kay, and Gregor S. Kijanka

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Single-cell imaging of the heat-shock response in colon cancer cells suggests that magnitude and length rather than time of onset determines resistance to apoptosis.
Lavanya Ramapathiran, Tytus Bernas, Franziska Walter, Linda Williams, Heiko Düssmann, Caoimhín G. Concannon, and Jochen HM Prehn

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Advances in immunotherapy for the treatment of glioblastoma.
Amanda Tivnan, Tatjana Heilinger, Ed C Lavelle, and Jochen H.M. Prehn

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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews, Margherita Annicchiarico-Petruzzelli, Alexey V Antonov, Eli Arama, Eric H Baehrecke, Nickolai A Barlev, Nicolas G Bazan, Francesca Bernassola, Mathieu J M Bertrand, Katiuscia Bianchi, Mikhail V Blagosklonny, Klas Blomgren, Christoph Borner, Patricia Boya, Catherine Brenner, Michelangelo Campanella, Eleonora Candi, Didac Carmona-Gutierrez, Francesco Cecconi, Francis K-M Chan, Navdeep S Chandel, Emily H Cheng, Jerry E Chipuk, John A Cidlowski, Aaron Ciechanover, Gerald M Cohen, Marcus Conrad, Juan R Cubillos-Ruiz, Peter E Czabotar, Vincenzo D'Angiolella, Ted M Dawson, Valina L Dawson, Vincenzo De Laurenzi, Ruggero De Maria, Klaus-Michael Debatin, Ralph J DeBerardinis, Mohanish Deshmukh, Nicola Di Daniele, Francesco Di Virgilio, Vishva M Dixit, Scott J Dixon, Colin S Duckett, Brian D Dynlacht, Wafik S El-Deiry, John W Elrod, Gian Maria Fimia, Simone Fulda, Ana J García-Sáez, Abhishek D Garg, Carmen Garrido, Evripidis Gavathiotis, Pierre Golstein, Eyal Gottlieb, Douglas R Green, Lloyd A Greene, Hinrich Gronemeyer, Atan Gross, Gyorgy Hajnoczky, J Marie Hardwick, Isaac S Harris, Michael O Hengartner, Claudio Hetz, Hidenori Ichijo, Marja Jäättelä, Bertrand Joseph, Philipp J Jost, Philippe P Juin, William J Kaiser, Michael Karin, Thomas Kaufmann, Oliver Kepp, Adi Kimchi, Richard N Kitsis, Daniel J Klionsky, Richard A Knight, Sharad Kumar, Sam W Lee, John J Lemasters, Beth Levine, Andreas Linkermann, Stuart A Lipton, Richard A Lockshin, Carlos López-Otín, Scott W Lowe, Tom Luedde, Enrico Lugli, Marion MacFarlane, Frank Madeo, Michal Malewicz, Walter Malorni, Gwenola Manic, Jean-Christophe Marine, Seamus J Martin, Jean-Claude Martinou, Jan Paul Medema, Patrick Mehlen, Pascal Meier, Sonia Melino, Edward A Miao, Jeffery D Molkentin, Ute M Moll, Cristina Muñoz-Pinedo, Shigekazu Nagata, Gabriel Nuñez, Andrew Oberst, Moshe Oren, Michael Overholtzer, Michele Pagano, Theocharis Panaretakis, Manolis Pasparakis, Josef M Penninger, David M Pereira, Shazib Pervaiz, Marcus E Peter, Mauro Piacentini, Paolo Pinton, Jochen H M Prehn, Hamsa Puthalakath, Gabriel A Rabinovich, Markus Rehm, Rosario Rizzuto, Cecilia M P Rodrigues, David C Rubinsztein, Thomas Rudel, Kevin M Ryan, Emre Sayan, Luca Scorrano, Feng Shao, Yufang Shi, John Silke, Hans-Uwe Simon, Antonella Sistigu, Brent R Stockwell, Andreas Strasser, Gyorgy Szabadkai, Stephen W G Tait, Daolin Tang, Nektarios Tavernarakis, Andrew Thorburn, Yoshihide Tsujimoto, Boris Turk, Tom Vanden Berghe, Peter Vandenabeele, Matthew G Vander Heiden, Andreas Villunger, Herbert W Virgin, Karen H Vousden, Domagoj Vucic, Erwin F Wagner, Henning Walczak, David Wallach, Ying Wang, James A Wells, Will Wood, Junying Yuan, Zahra Zakeri, Boris Zhivotovsky, Laurence Zitvogel, Gerry Melino, and Guido Kroemer

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The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.
Steven Carberry, Beatrice D'Orsi, Naser Monsefi, Manuela Salvucci, Orna Bacon, Joanna Fay, Markus Rehm, Deborah McNamara, Elaine W Kay, and Jochen H M Prehn

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Pleiotropic activity of systemically delivered angiogenin in the SOD1
Martin Crivello, Saidhbhe L. O'Riordan, Ina Woods, Sarah Cannon, Luise Halang, Karen S. Coughlan, Marion C. Hogg, Sebastian A. Lewandowski, and Jochen HM Prehn

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miR-222 isoforms are differentially regulated by type-I interferon.
Charlotte Nejad, Katherine A Pillman, Katherine J Siddle, Geneviève Pépin, Minna-Liisa Änkö, Claire E McCoy, Traude H Beilharz, Lluís Quintana-Murci, Gregory J Goodall, Cameron P Bracken, and Michael P Gantier

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Radiology reporting of obesity: a survey of patient and clinician attitudes.
Timothy E. Murray, S D. Ma, Frank Doyle, and Michael J. Lee

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Targeting the proteasome in epilepsy.
Tobias Engel, Jose J Lucas, and David C. Henshall

 

Examining the In Vitro Efficacy of the IAP Antagonist Birinapant as a Single Agent or in Combination With Dacarbazine to Induce Melanoma Cell Death.
Vesna Vetma, Jan Rožanc, Emilie M Charles, Christian T Hellwig, Leonidas G Alexopoulos, and Markus Rehm

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Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells.
Amanda Tivnan, Tatjana Heilinger, Joanne M Ramsey, Gemma O'Connor, Jenny L Pokorny, Jann N Sarkaria, Brett W Stringer, Bryan W Day, Andrew W Boyd, Ella L Kim, Holger N Lode, Sally-Ann Cryan, and Jochen H.M. Prehn

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SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival.
Beatrice Mohelnikova-Duchonova, Ondrej Strouhal, David J Hughes, Ivana Holcatova, Martin Oliverius, Zdenek Kala, Daniele Campa, Cosmeri Rizzato, Federico Canzian, Raffaele Pezzilli, Renata Talar-Wojnarowska, Ewa Malecka-Panas, Cosimo Sperti, Carlo Federico Zambon, Sergio Pedrazzoli, Paola Fogar, Anna Caterina Milanetto, Gabriele Capurso, Gianfranco Delle Fave, Roberto Valente, Maria Gazouli, Giuseppe Malleo, Rita Teresa Lawlor, Oliver Strobel, Thilo Hackert, Nathalia Giese, Pavel Vodicka, Ludmila Vodickova, Stefano Landi, Francesca Tavano, Domenica Gioffreda, Ada Piepoli, Valerio Pazienza, Andrea Mambrini, Mariangela Pedata, Maurizio Cantore, Franco Bambi, Stefano Ermini, Niccola Funel, Radmila Lemstrova, and Pavel Soucek

*Updated as of 04/19/18.