Peer Reviewed

1

Document Type

Article

Publication Date

15-6-2016

Keywords

Mouse, Brain, Hippocampus, Proteins, Proteomics, Mass spectrometry, Omega-3 deficiency.

Funder/Sponsor

David R. Cotter is funded by the Health Research Board, Clinical Scientist Award. Ger Cagney is funded by Science Foundation Ireland.

Comments

The original article is available at www.sciencedirect.com

Abstract

This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.

Disciplines

Medicine and Health Sciences | Psychiatry and Psychology

Citation

English JA, Scaife C, Harauma A, Focking M, Wynne K, Cagney G, Moriguchi T, Cotter DR. Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation. Data in Brief. 2016;7:341-3.

PubMed ID

26977433

DOI Link

10.1016/j.dib.2015.12.057

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.

Share

COinS