Mouse, Brain, Hippocampus, Proteins, Proteomics, Mass spectrometry, Omega-3 deficiency.
David R. Cotter is funded by the Health Research Board, Clinical Scientist Award. Ger Cagney is funded by Science Foundation Ireland.
This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 ), in which a more comprehensive interpretation and analysis of the data is given.
Medicine and Health Sciences | Psychiatry and Psychology
English JA, Scaife C, Harauma A, Focking M, Wynne K, Cagney G, Moriguchi T, Cotter DR. Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation. Data in Brief. 2016;7:341-3.
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