Peer Reviewed

1

Document Type

Article

Publication Date

28-7-2017

Keywords

Aza Compounds, Boron Compounds, Colon, Dose-Response Relationship, Drug, Fluorescent Dyes, Humans, Molecular Structure, Porphobilinogen, Spectroscopy, Near-Infrared, Structure-Activity Relationship

Funder/Sponsor

Science Foundation Ireland grant number 11/PI/1071(T).

Comments

The original article is available at www.sciencedirect.com

Abstract

The use of near-infrared fluorescence for in vivo research and intraoperative clinical imaging is rapidly expanding, with new applications being proposed and developed. While imaging hardware and software have significantly progressed in recent times, the molecular fluorescent agents remain a limiting factor. In this report, the design, synthesis, photophysical characterization and bio-medical imaging assessment of two new NIR-fluorophores based on the BF

Disciplines

Chemistry | Medicinal-Pharmaceutical Chemistry | Medicine and Health Sciences

Citation

Daly HC, Sampedro G, Bon C, Wu D, Ismail G, Cahill RA, O'Shea DF. BF2-azadipyrromethene NIR-emissive fluorophores with research and clinical potential. European Journal of Medicinal Chemistry. 2017;135:392-400

PubMed ID

28460313

DOI Link

10.1016/j.ejmech.2017.04.051

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.

Share

COinS