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Submissions from 2017

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Directed self-assembly of fluorescence responsive nanoparticles and their use for real-time surface and cellular imaging., Shane Cheung and Donal F. O'Shea

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Polymer brush decorated nanoparticles immobilised on polymer monoliths for enhanced biopolymer elution, M Iacono, D Connolly, and Andreas Heise

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Platinum(iv) oxaliplatin-peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells., Aoife M. McKeon, Janis Noonan, Marc Devocelle, Brona M. Murphy, and Darren M. Griffith

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Mandelic acid derived ionic liquids: synthesis, toxicity and biodegradability, Hannah Prydderch, Annette Haib, Marcel Spulak, Brid Quilty, Klaus Kummerer, Andreas Heise, and Nicholas Gathergood

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Fluorogenic NIR-Probes Based on 1,2,4,5-Tetrazine Substituted BF2-Azadipyrromethenes, Dan Wu and Donal F. O'Shea

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Eradication of Staphylococcus aureus Biofilm Infections Using Synthetic Antimicrobial Peptides., Marta Zapotoczna, Éanna Forde, Siobhan Hogan, Hilary Humphreys, James P O'Gara, Deirdre Fitzgerald-Hughes, Marc Devocelle, and Eoghan O'Neill

Submissions from 2016

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Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis., Éanna Forde, André Schütte, Emer P. Reeves, Catherine M. Greene, Hilary Humphreys, Marcus Mall, Deirdre Fitzgerald-Hughes, and Marc Devocelle

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Azadipyrromethenes: from traditional dye chemistry to leading edge applications., Yuan Ge and Donal F. O'Shea

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Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time., Marco Grossi, Marina Morgunova, Shane Cheung, Dimitri Scholz, Emer Conroy, Marta Terrile, Angela Panarella, Jeremy C. Simpson, William M. Gallagher, and Donal F. O'Shea

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Fabrication of a GMA-co-EDMA Monolith in a 2.0 mm i.d. Polypropylene Housing., Marcello Iacono, Damian Connolly, and Andreas Heise

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Polymeric prodrug combination to exploit the therapeutic potential of antimicrobial peptides against cancer cells., G J. Kelly, A Foltyn-Arfa Kia, F Hassan, S O'Grady, Maria P. Morgan, B S. Creaven, S McClean, Judith H. Harmey, and Marc Devocelle

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Novel class of Bi(iii) hydroxamato complexes: synthesis, urease inhibitory activity and activity against H. pylori., Donal M. Keogan, Brendan Twamley, Deirdre Fitzgerald-Hughes, and Darren M. Griffith

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Synthesis of polymeric bismuth chlorido hydroxamato complexes; X-ray crystal structure and antibacterial activity of a novel Bi(lll) salicylhydroxamato complex, Donal M. Keoghan, Lauren E. Fagan, Thayse Marques Passos, Helge Müller-Bunz, Bríd Quilty, and Darren M. Griffith

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Novel Improved Synthesis of HSP70 Inhibitor, Pifithrin-μ. In Vitro Synergy Quantification of Pifithrin-μ Combined with Pt Drugs in Prostate and Colorectal Cancer Cells., Aoife M. McKeon, Alan Egan, Jay Chandanshive, Helena McMahon, and Darren M. Griffith

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A novel dual-functioning ruthenium(II)-arene complex of an anti-microbial ciprofloxacin derivative - Anti-proliferative and anti-microbial activity., Ziga Ude, Isolda Romero-Canelón, Brendan Twamley, Deirdre Fitzgerald Hughes, Peter J. Sadler, and Celine J. Marmion

Submissions from 2015

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Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection., Aisling F. Brown, Alison G. Murphy, Stephen J. Lalor, John M. Leech, Kate M. O'Keeffe, Micheál Mac Aogáin, Dara P. O'Halloran, Keenan A. Lacey, Mehri Tavakol, Claire H. Hearnden, Deirdre Fitzgerald-Hughes, Hilary Humphreys, Jérôme P. Fennell, Willem J. van Wamel, Timothy J. Foster, Joan A. Geoghegan, Ed C. Lavelle, Thomas R. Rogers, and Rachel M. McLoughlin

Submissions from 2014

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Bu4N(+) Alkoxide-Initiated/Autocatalytic Addition Reactions with Organotrimethylsilanes., Manas Das and Donal F. O'Shea

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Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions., Fergal J. Duffy, Marc Devocelle, David R. Croucher, and Denis C. Shields

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Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis., Éanna Forde, Hilary Humphreys, Catherine M. Greene, Deirdre Fitzgerald-Hughes, and Marc Devocelle

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Current and Potential Applications of Bismuth-Based Drugs., Donal M. Keogan and Darren M. Griffith

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Poly(Ethylene glycol)-based backbones with high peptide loading capacities., Aoife O'Connor, Jean-Noel Marsat, Annachiara Mitrugno, Tom Flahive, Niamh Moran, David Brayden, and Marc Devocelle

Submissions from 2012

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β-Lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria., Stephane Desgranges, Carol C. Ruddle, Liam P. Burke, Tara M. McFadden, John E. O'Brien, Deirdre Fitzgerald-Hughes, Hilary Humphreys, Timothy P. Smyth, and Marc Devocelle

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Targeted antimicrobial peptides., Marc Devocelle

Submissions from 2011

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In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens., Stephane Desgranges, Florie Le Prieult, Alan Daly, Marian Brennan, Dilip K. Rai, Anusha P. Subasinghage, Chandralal M. Hewage, Sally-Ann Cryan, Catherine M. Greene, Noel G. McElvaney, Timothy P. Smyth, Deirdre Fitzgerald-Hughes, Hilary Humphreys, and Marc Devocelle

Submissions from 2009

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A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity., Darren Griffith, Maria P. Morgan, and Celine J. Marmion

Submissions from 2008

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Monohydroxamic acids and bridging dihydroxamic acids as chelators to ruthenium(III) and as nitric oxide donors: syntheses, speciation studies and nitric oxide releasing investigations., Darren M. Griffith, Krystyna Krot, Jedd Comiskey, Kevin B. Nolan, and Celine J. Marmion

Submissions from 2005

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A peptide corresponding to the neuropilin-1-binding site on VEGF(165) induces apoptosis of neuropilin-1-expressing breast tumour cells., Martin P. Barr, Anne Marie Byrne, Angela M. Duffy, Claire M. Condron, Marc Devocelle, Patrick Harriott, David J. Bouchier-Hayes, and Judith H. Harmey