Follow

Theses/Dissertations from 2011

PDF

Modulation of apoptosis signalling by proteasome inhibition : a single cell analysis, Maike A. Laussmann

PDF

The use of collagen-based bone graft substitutes for orthopaedic regenerative medicine., Frank G. Lyons

PDF

Gait impairment in cervical spondylotic myelopathy: Analysis, impact on function, and effect of surgical intervention, Ailish Marie Malone

PDF

Identifying new transcriptional targets for SRC-1 in breast cancer, Damian McCartan

PDF

Cardiovascular Genetics: Candidate Gene, Candidate Pathway and Whole Genome Analyses, Nina McCarthy

PDF

Genome-wide mapping of MYCN transcription factor binding sites and identification of clinically relevant targets in neuroblastoma., Derek Murphy

PDF

Estrogen receptor-coactivator interactions in resistance to aromatase inhibitor treatment for breast cancer., Jane O'Hara

PDF

Histological evaluation of putative biomarkers in prostate cancer, Gillian O'Hurley

PDF

Real-time imaging analysis and functional characterisation of transcription factor NF-kappaB activation in a model of excitotoxic injury in rat neurons., Robert F. Schwamborn

PDF

Characterisation of angiogenin uptake and signalling in astrocytes, Alexandra Skorupa

PDF

The role of tyrosine phosphorylation in the regulation of Ro52, Kevin B. Stacey

PDF

Research in pharmacy education - lessons from programme design and development at a new School of Pharmacy, Judith Strawbridge

PDF

The role of T-cell immunoglobulin and mucin-domain-containing molecules in inflammation in the cystic fibrosis airways, Isabel Vega-Carrasca

PDF

The Role of HIF Hydroxylases in the Regulation of Colonic Epithelial Ion Transport, Joseph Bernard Jude Ward

PDF

Use of Aliphatic and Aromatic Styryl Isoxazoles as Versatile Intermediates for the Synthesis of Peptidomimetics, Drug Molecules and Optically Active Building Blocks for Organic Synthesis, Robert Wells

PDF

Correlation Analysis of Treatment Sensitivity and Protein Expresson of pro- and anti-apoptotic Proteins & the Role of the BH3-only Protein Bim during Apoptosis of malignant Gliomas, Birgit Claudia Weyhenmeyer

Theses/Dissertations from 2010

PDF

The role of lipoxin A4 in regulating ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium, Mazen Al-Alawi

PDF

Effect of gene knockout and NMDA receptor modulation on cell survival and neuronal stem cell fate in in vitro and in vivo models of excitotoxicity., Eva C. Bunk

PDF

Bidirectional receptor crosstalk in breast cancer: the role of c-myc and coregulatory proteins and future implications for cancer treatment., Dearbhaile C. Collins

PDF

Modified host defence peptides as beta-lactamase-dependent antibiotic prodrug candidates., Stephane Desgranges

PDF

The effect of the X-linked Inhibitor-of-Apoptosis Protein on the release of Smac from the mitochondria during Apoptosis, Lorna Flanagan

PDF

RuvB12 as a regulator of hTERT, Padraic Flavin

PDF

Functional studies of microRNAs involved with ATRA induced differentiation of neuroblastoma cells, Niamh Foley

PDF

Real-Time Single Cell Analyses of Apoptosis Initiation and Execution Signalling in Human Cancer Cells, Christian Timotheus Hellwig

PDF

The molecular mechanisms of streptococcus gordonii-platelet interactions involved in the pathogenesis of cardiovascular infection, Ciara Keane

PDF

Analysis of osteogenesis on a novel collagen glycosaminoglycan scaffold- in vitro application for bone tissue engineering, Michael Keogh

PDF

Design and evaluation of novel anti-tubulin agents selectively targeting parasitic tubulin, Christine Mara

PDF

Molecular epidemiology of carriage and disease associated strains of serogroup C Neisseria meningitidis, in the Irish Republic following the introduction of the meningococcal conjugate vaccine., Robert Martin Mulhall

PDF

The effect of mean pore size in collagen-glycosaminoglycan scaffolds on cell migration and differentiation for bone tissue engineering applications, Ciara M. Murphy

PDF

Examination of formulation and process factors on the characteristics of fast dissolving and fast disintegrating tablets manufactured by a direct compression process., Ritesh M. Pabari

PDF

Towards the Asymmetric Synthesis of 1,2-Oxazines, Linda Piras

PDF

Detection and characterisation of heat shock responses in relation to cell death signaling in human cancer cells, Lavanya Ramapathiran

PDF

Optimisation, validation and application of quantitative magnetic resonance image analysis techniques to study the endophenotypic potential of brain morphology in temporal lobe epilepsy, Catherine Scanlon

PDF

Bioengineered microparticles for controlled drug delivery to the lungs, Neeraj Sivadas

PDF

In-vitro osteogenesis is affected by composition and stiffness of collagen-GAG scaffold., Claire M. Tierney

Theses/Dissertations from 2009

PDF

New carboxylate and hydroxamate inhibitors of prostaglandin-H-synthase and their metal complexes, Ahmed Al Agha

PDF

Development of novel collagen-calcium phosphate scaffolds suitable for bone tissue-engineering and bone repair, Amir A. Al-Munajjed

PDF

Gene expression profiling of molecular target genes which are regulated by hepatocyte nuclear factor 1 Alpha (HNF1A) in rat insulin-secreting cells: role in HNF1A-MODY, Caroline Bonner

PDF

The role of cytosolic phospholipase A2 in the rapid oestrogen-induced signalling responses in breast cancer cells, Francesco Caiazza

PDF

Extrinsic and intrinsic regulation of breast cancer progression - promoting an aggressive phenotype via alterations in cellular populations and subcellular compartments, Simona Donatello

PDF

Potential hazards in the medication use process at the hospital community interface and a strategy to reduce them., Tamasine Grimes

PDF

Skin and bone : the effect of age and estrogen deficiency., Claragh Healy

PDF

An investigation of the neurocognitive phenotype of 22Q11.2 deletion syndrome across developmental stages., Sarah A. Howley

PDF

Design, synthesis and antibiotic susceptibility evaluation of prodrugs of peptides and anti-inflammatory agens for colonic delivery, David Andrew Kennedy

PDF

Anatomists and geometers : a selection from the published work., T Clive Lee

PDF

The effect of repositioning 3 hourly at night, using the 30 degree tilt, on the incidence of pressure ulcers, in older persons at risk of pressure ulcer development hospitalised in long-term care settings, Zena EH Moore

PDF

Assessing platelet function using a novel microtitre platelet aggregation assay, Aaron Peace

PDF

The role of Bcl-2 homology domain (BH) 3-only proteins in stress-induced cell death of mouse neocortical neurons associated with ischemic brain injury, Liam Patrick Tuffy

PDF

A study of the genotoxic implications and enhancement technologies for solar disinfection (SODIS) of drinking water, Eunice M. Ubomba-Jaswa

Theses/Dissertations from 2008

PDF

Studies on the generation of chemical diversity using hetero Diels Alder reactions and polyfunctional scaffolds, Simone Bruschi

PDF

A study of the role of genetic factors in the classification of distinct multiple sclerosis clinical phenotypes, Tania Jawad