Date of Award

Summer 2018

Document type


Degree Name

PhD (Doctor of Philosophy)

First Supervisor

Professor Andreas Heise

Second Supervisor

Professor Sally-Ann Cryan


This chapter will detail the beginnings and current state of NCA derived synthetic polypeptides, the role of multifunctional initiators in the development of complex star shaped polypeptide architectures and their associated properties, the synthetic approaches undertaken for the design of hydrogelating materials from the NCA ring opening polymerisation; detailing the dependence on amino acid composition and architecture; followed by a brief introduction to 3D printing and its potential relevance in the fabrication of polypeptide hydrogels.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.

File Size

8.62 MB


A thesis submitted for the degree of Doctor of Philosophy from the Royal College of Surgeons in Ireland in 2018.