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Theses/Dissertations from 2017

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Cardiovascular and temperature actions of cathinones, Hadeel A. Alsufyani

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3.0 Tesla MRI analysis of the Intra-Uterine Growth Restricted Infant Brain - Comparison of Infants with Normal and Abnormal Antenatal Doppler's., Michael A. Boyle

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The role of carer stress in acute and long-term care utilisation by community-dwelling older people, Nora-Ann Donnelly

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Why is blood group a risk marker for myocardial infarction?, Eimear Dunne

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Feasibility analysis of emergency department key performance indicators in Ireland, Aileen M. McCabe

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Quality of End-of-Life Care in Acute and Community Hospitals from Relatives' Perspectives and Stakeholder Perceptions of the Potential of their Views to Inform Positive Change in Care, Siobhan E. McCarthy

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Medication Reconciliation: the primary secondary care interface, Patrick Redmond

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The Importance of Inhaler Technique in Measuring and Calculating Inhaler Adherence, and its Clinical Outcomes, Imran Sulaiman

Theses/Dissertations from 2016

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Type 2 diabetes and breast cancer - the role of hyperinsulinaemia in breast cancer development and mortality, Emily Jane Gallagher

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Trespassing the defensive lines cardiovascular infection, Cormac J. McDonnell

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Multi-functional Copper(II) Drug Candidates as Potential Anti-Cancer Agents, Tadhg James Patrick Mc Givern

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The influence of novel alpha-1 antitrypsin protein binding partners on inflammation and the clinical phenotype in alpha-1 antitrypsin deficiency, Michael E. O'Brien

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Exploring Choice, Home and Health Service Utilisation For People Ageing With An Intellectual Disability During A Time Of Housing Relocation And Transition, Mary-Ann O'Donovan

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Natural Honey to Eradicate Nasal Methicillin resistant Staphylococcus aureus (MRSA) A Randomised Control Trial, Toney Thomas Poovelikunnel

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Collagen and Elastin based Tissue Engineered Vascular Grafts, Alan J. Ryan

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Factors Influencing the High School Students' Choice of a Nursing Career in Bahrain: Development of a Best Practice Model for Nursing Recruitment, Eman A. Tawash

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Predicting adverse health outcomes in older community-dwelling adults: a prospective cohort study, Emma Wallace

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Power, culture and researcher identity: an ethos of international academic 'north-south' public health research, Aisling Walsh

Theses/Dissertations from 2015

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Characterization of a protein: protein interaction between RNF181 and the platelet integrin, αIIbβ3, Seamus Allen

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The Dynamic Platelet Function Assay (DPFA): Assessment of platelet translocation behaviour on von Willebrand Factor (VWF) in pregnancy, neonates and adults, Jonathan James Cowman

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Novel Host Defence Peptide Prodrugs for use in Cystic Fibrosis, Eanna Forde

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Investigation of existing and novel therapeutics to treat intravascular catheter-related infections caused by staphylococci using a combination of in vitro and animal models, Siobhan Hogan

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Expression, Function and Targeting of the ATP-gated P2X7 receptor in epilepsy, Alba Jimenez Pacheco

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The Role of Bid as a positive regulator of mutant SOD1 - induced TLR4 - NF-ҡB signalling in microglia, Sinéad Kinsella

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Bile acids regulate colonic epithelial barrier function: implications for pathogenesis and therapy of inflammatory bowel disease, Natalia Katarzyna Lajczak

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The Role of Notch Receptors in the Alloimmune Response, Ciara N. Magee

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"I found myself staying" - A case study of the job embeddedness and retention of qualified health workers in rural and remote areas of Uganda, Everd B. Maniple

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Dysregulation of cytokine and monocyte function in systemic lupus erythematosus, Eoghan M. McCarthy

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Paediatric Non-Invasive Pneumococcal Serotypes, Antimicrobial Susceptibilities and Virulence Factors in the Era of Conjugate Vaccines, Martha McElligott

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Development of a microRNA Delivery Scaffold System for Bone Tissue Engineering, Irene Mencía Castaño

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The microbial quality and the use of sodis to treat harvested rainwater in rural areas of Uganda case study: Makondo-Lwengo Masaka, Rosemary Nalwanga

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Development of Cargo-specific Delivery Systems for the Treatment of Myocardial Infarction, Hugh O'Neill

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Factors influencing GP Referrals to Symptomatic Breast Units in Ireland, Niamh O'Rourke

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Specialized Pro-resolution Mediators in Cystic Fibrosis Lung Disease, Fiona C. Ringholz

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The Use of Coercion in Clinical Mental Health Practice, Stephen Shannon

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Discovery of small molecule FcγRIIa Antagonists, Michael Thai Trung King

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The In Vivo functionality of collagen-based scaffolds for orthopaedic tissue repair, Emmet M. Thompson

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Combining magnetic resonance imaging and genome-wide genetic mapping in epilepsy, Christopher D. Whelan

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Altered membrane lipid raft structure: A potential factor leading to dysregulated neutrophil activity in airways disease., Michelle M. White

Theses/Dissertations from 2014

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Peptide Modified Probes and Surfaces for Protein Sensing and Platelet Capture, Kellie Adamson

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Investigating novel mechanisms of metastasis in endocrine resistant breast cancer., Jarlath Bolger

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The functional roles of GPVI, GPIba, and PARs in the generation of platelet-derived reactive oxygen species., Naadiya Carrim

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Effectiveness of medicines review with web-based pharmaceutical treatment algorithms in reducing potentially inappropriate prescribing in older people in primary care: a cluster randomised trial (OPTI-SCRIPT study), Barbara Clyne

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In vitro and in vivo elucidation of AMPK as a new therapeutic target in Amyotrophic Lateral Sclerosis, Karen Coughlan

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The role of osteoprotegerin and receptor activator of nuclear factor kappa-betta ligand in vascular calcification and the influence of insulin and liraglutide on this process in type 2 diabetes mellitus., Colin Davenport

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Development of Phase Transfer Catalysed Cyclopropanation and Related Processes, Claudia Del Fiandra

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Determining the contributions of caspase-2 and caspase-8 to intracellular protease activities during apoptosis, Maria Eugenia Delgado

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Studies concerning the preparation of enantiopure intermediates for the manufacture of diagnostics, Colm James Duffy

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Myelin Abnormalities in Schizophrenia: Insights from Proteomic Investigations of Post-Mortem Schizophrenia and Pre-Clinical Animal Models, Lorna Farrelly

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Exploring the effects of Cadherin-derived Peptides on Platelet and Endothelial Cell Function, Kalyan Golla

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Physiological Impact of Lipoxin A4 on Cystic Fibrosis Bronchial Epithelium, Gerard Higgins

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Quality of life of Bahraini women with breast cancer, Ghufran Ahmed Jassim

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Peptide Prodrugs: Using Host Defence Peptides as Therapeutic Anticancer Agents, Graeme Joseph James Kelly

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The Actions of Ursodeoxycholic Acid and its derivatives on Colonic Epithelial Transport and Barrier Function, Orlaith B. Kelly

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Mathematical modelling of stress signalling and cell fate during genotoxic stress, Andreas U. Lindner

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Investigation into the potential of Human Amniotic Fluid-Derived Stem Cells for use in Orthopaedic Tissue Engineering, Cai Lloyd-Griffith

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Individual Platelet Adhesion (iPA): A novel assay of platelet function, Ana Lopez Alonso

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The Impact of a Changed Approach to Analgesia and Sedation Management in the Paediatric Intensive Care Unit, Claire Magner

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Investigation into the role of La/SS-B in Interferon regulation and its relevance in health and human disease, Rebecca G. Mahony

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Heritable and environmental determinants of platelet response to acetylsalicylic acid/, Andrew Maree

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Changes in the Ultrastructural Features of Estrogen Deficient Ovine Bone, Peter Mauer

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Effectiveness of conventional versus virtual reality based vestibular rehabilitation in the treatment of dizziness, gait and balance impairment in adults with unilateral peripheral vestibular hypofunction, Dara Meldrum

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Time to hospital presentation in acute ischaemic stroke, Lisa Mellon

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Molecular exploration of tumour cell-induced platelet activation and its relevance in the treatment of cancer., Annachiara Mitrugno

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An evaluation of impairment, mobility and quality of life in Polio survivors, change in muscle strength over time and the effects of an arm ergometry aerobic exercise programme., Deirdre E. Murray

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Phenotypic characterisation of a novel mutant mouse with target deletion of dysbindin-1A in relation to the schizophrenia risk gent DTNBP1., Emilie Petit

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Controlled Release of Bioactive Molecules from Collagen-Based Scaffolds for Bone Repair, Elaine Quinlan

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Synthesis of unnatural C-nucleosides for DNA-based catalysis., James J. Reck

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Organocatalysis via covalent and non covalent bonding: synthetic applications and mechanistic insights., Diana Salazar Illera

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Studies Concerning the Use of Activated Alkenes in Enantioselective Reactions., Michela Scagnetti

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Effects of schizophrenia, bipolar disorder, and haloperidol on the hippocampus: a proteomic approach., Klaus O. Schubert

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Communicable disease screening for asylum seekers and refugees in Ireland: an analysis of professional stakeholders’ insights into knowledge into action, Gemma Smith

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Intrauterine Fetal Growth Restriction - New Insights into Prenatal Detection, Definition, Surveillance and Delivery, Julia Unterscheider

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Real time single cell imaging of ER stress responses, Franziska Walter

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Analysis of the Effects of HSF1 Inhibition in Colon Cancer, Linda Marie Williams

Theses/Dissertations from 2013

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The Application of Quantitative Magnetic Resonance Imaging (QMRI) to Identify Neuroanatomical Endophenotypes in Epilepsy, Saud Alhusaini

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A School-based Trial Protocol in Community Promotion of Solar Water Disinfection (SODIS): A Case Study of Ndagwe Sub County, Central Uganda, Jacent Kamuntu Asiimwe

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A novel role of lipid rafts in regulating CD44-dependent breast cancer cell migration., Irina S. Babina

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The epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and an investigation of a novel therapeutic peptide conjugate., Liam Burke

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AMP-Activated Protein Kinase (AMPK) Activation and Signalling Following Neuronal Excitotoxicity, Niamh M C Connolly

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Elucidating the role of microRNA-497 and WEE1 in neuroblastoma disease pathogenesis., Laura M. Creevey

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Public policy and health behaviour: An investigation of tobacco control policy and smoking in Ireland, Laurie Michelle Currie

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The role of platelets in the pathology of cancer., Karl Egan

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An Investigation of Cannabis Use and Childhood Trauma in Relation to Psychotic Symptoms and Their Outcomes: a Population-Based Follow-up Study of Irish Adolescents, Michelle Harley

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Functional analysis of miRNA in chemotherapy resistant neuroblastoma., Harry Harvey

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The Role of Micrornas in Alpha-1 Antitrypsin Deficiency Disease., Tidi M. Hassan

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Modulation of Chloride Secretion by Bile Acids in Airway Epithelial Cells., Siobhan M. Hendrick

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The development of novel siRNA nanoparticles for delivery to pulmonary epithelial cells, Alan J. Hibbitts

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The role of oestrogen induced signalling in the suppression of malignant mesothelioma cell growth., Cormac Jennings

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Molecular signalling pathways involved in AMPK-mediated neuronal preconditioning and optimisation of a high content screening assay to monitor excitotoxic neuronal death., Ujval A. Kumar

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Elucidating the role of metastasis suppressor microRNA-335 in neuroblastoma disease pathogenesis., Jennifer Lynch

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The "humanisation" of medicine? : the feminisation of medicine: a qualitative study of the career experiences of female doctors and implications for human resources management in Ireland., Sara McAleese

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Genome-wide mapping of markers for epilepsy predisposition and treatment., Mark McCormack

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A role for microRNA-29a mediating ER stress-induced apoptosis in neuronal cells in the mouse central nervous system., Katie Nolan

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Novel peptide and poly(ethylene oxide)-based structures for drug delivery systems, Aoife O'Connor

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Novel multi-functional metallo-drug candidates with enhanced selectivity and activity towards cancer cells., James Parker

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Estrogen regulation of the Potassium Channel KCNQ1:KCNE3 in Colonic Epithelium, Raphael Rapetti-Mauss

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Investigation into the Role and Regulation of Tripartite Motif-containing protein 21 (TRIM21) in Systemic Lupus Erythematosus, Siobhán Smith

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Pathways to human platelet activation : convergence of streptococcus pneumoniae and streptococcus oralis at a universal actor, Fc gamma RIIA, Dorothea O. Tilley

Theses/Dissertations from 2012

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Stereoselective Preparation of Enantiopure Abasic Nucleosides and 4-Nitroisoxazoles, Gea Bellini