Peer Reviewed

1

Document Type

Article

Publication Date

1-6-2008

Keywords

Cryopreservation, Embryo Implantation, Embryo Transfer, Female, Fertilization in Vitro, Humans, Infertility, Female, Pregnancy, Pregnancy Rate, Pregnancy, Multiple, Reproductive Techniques, Assisted, Zygote

Comments

The original article is available at imj.ie

Abstract

Cryopreservation of zygotes and subsequent thaw and transfer is an established ART treatment. We assessed if success rates frozen-thawed (day 2) zygotes are comparable with the outcome in fresh cycles of treatment. We performed a prospective follow-up and analysis of all frozen (FZT) and fresh cycles of treatment during a 12 months period. One hundred and nineteen patients in the frozen-thawed and 652 in the fresh group had a transfer. The overall thaw-survival rate was 71.7%. Clinical pregnancy rates per thaw and transfer were respectively 15.1% and 21% in the frozen and 29.1% (per transfer) in the fresh group. Implantation rates in fresh and frozen cycles were 16% and 12.3% respectively. The pregnancy loss rate was higher in the FZT group (29% vs. 18.3%). Cryopreservation of good quality zygotes, after fresh transfer offers optimal success rates in subsequent frozen treatment. It also encourages consideration of elective single zygote transfers.

Disciplines

Medicine and Health Sciences | Obstetrics and Gynecology

Citation

Mocanu EV, Cottell E, Waite K, Hennelly B, Collins C, Harrison RF. Frozen-thawed transfer cycles: are they comparable with fresh? Irish Medical Journal. 2008;101(6):181-4.

PubMed ID

18700513

Creative Commons License

Creative Commons License
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