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Submissions from 2019

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What Really Matters to You? A Study of Public Perspectives on General Practice in Ireland, John Brennan, Marie Bourke, Reamonn O’Donnchadha, and Anne Mulrooney

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Statins for the primary prevention of cardiovascular disease: an overview of systematic reviews., Paula Byrne, John Cullinan, Amelia Smith, and Susan M. Smith

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Association between gaps in antihypertensive medication adherence and injurious falls in older community-dwelling adults: a prospective cohort study., Paul Dillon, Susan M. Smith, Paul Gallagher, and Grainne Cousins

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Prescriber Variation in Relation to Prescribing Trends within the Preferred Drugs Initiative in Ireland (2012-2015): An Interrupted Time-Series Study Using Latent Curve Models., Ronald McDowell, Kathleen Bennett, Frank Moriarty, Sarah Clarke, Michael Barry, and Tom Fahey

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Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models., Frank Moriarty, Caitriona Cahir, Kathleen Bennett, and Tom Fahey

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Unintended discontinuation of medication following hospitalisation: a retrospective cohort study., Patrick Redmond, Ronald McDowell, Tamasine C C. Grimes, Fiona Boland, Ronan McDonnell, Carmel Hughes, and Tom Fahey

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Predicting poorer health outcomes in older community-dwelling patients with multimorbidity: prospective cohort study assessing the accuracy of different multimorbidity definitions., Maxime Sasseville, Susan M. Smith, Lisa Freyne, Ronald McDowell, Fiona Boland, Martin Fortin, and Emma Wallace

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Developing outcome, process and balancing measures for an emergency department longitudinal patient monitoring system using a modified Delphi., Marie E. Ward, Abel Wakai, Ronald McDowell, Fiona Boland, Eoin Coughlan, Moayed Hamza, John Browne, Ronan O'Sullivan, Una Geary, Fiona McDaid, Éidín Ní Shé, Frances J. Drummond, Conor Deasy, and Eilish McAuliffe

Submissions from 2018

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The PIPc Study-application of indicators of potentially inappropriate prescribing in children (PIPc) to a national prescribing database in Ireland: a cross-sectional prevalence study., Emma Barry, Frank Moriarty, Fiona Boland, Kathleen Bennett, and Susan M. Smith

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Antivirals for influenza-Like Illness? A randomised Controlled trial of Clinical and Cost effectiveness in primary CarE (ALIC4 E): the ALIC4 E protocol., Emily Bongard, Alike W. van der Velden, Johanna Cook, Ben Saville, Philippe Beutels, Rune Munck Aabenhus, Curt Brugman, Slawomir Chlabicz, Samuel Coenen, Annelies Colliers, Melanie Davies, Muireann De Paor, An De Sutter, Nick A. Francis, Dominik Glinz, Maciek Godycki-Ćwirko, Herman Goossens, Jane Holmes, Margareta Ieven, Menno de Jong, Morten Lindbaek, Paul Little, Frederico Martinón-Torres, Ana Moragas, József Pauer, Markéta Pfeiferová, Ruta Radzeviciene-Jurgute, Pär-Daniel Sundvall, Antoni Torres, Pia Touboul, Dionyssios Varthalis, Theo Verheij, and Christopher C. Butler

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Cross-sectional analysis of the prevalence and predictors of statin utilisation in Ireland with a focus on primary prevention of cardiovascular disease., Paula Byrne, John Cullinan, Catríona Murphy, and Susan M. Smith

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Supporting prescribing in Irish primary care: protocol for a non-randomised pilot study of a general practice pharmacist (GPP) intervention to optimise prescribing in primary care., Karen Cardwell, Barbara Clyne, Frank Moriarty, Emma Wallace, Tom Fahey, Fiona Boland, L McCullagh, S Clarke, K Finnigan, M Daly, M Barry, S M. Smith, and General Practice Pharmacist (GPP) Study Group

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Effectiveness of early assessment and intervention by interdisciplinary teams including health and social care professionals in the emergency department: protocol for a systematic review., Marica Cassarino, Katie Robinson, Rosie Quinn, Breda Naddy, Andrew O'Regan, Damien Ryan, Fiona Boland, Marie E. Ward, Rosa McNamara, Gerard McCarthy, and Rose Galvin

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A Cross-Sectional Study of Antibiotic Prescribing for Childhood Upper Respiratory Tract Infections in Irish General Practice, Fiachra Maguire, Mark E. Murphy, M Rourke, F Morgan, G Brady, E Byrne, and Michael E. O’Callaghan

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An evaluation of prescribing trends and patterns of claims within the Preferred Drugs Initiative in Ireland (2011-2016): an interrupted time-series study., Ronald McDowell, Kathleen Bennett, Frank Moriarty, Sarah Clarke, Michael Barry, and Tom Fahey

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The Prevalence of Severe Sepsis or Septic Shock in an Irish Emergency Department., Ciara McNevin, Dermot McDowell, Fidelma Fitzpatrick, R O'Sullivan, and Abel Wakai

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Seasonal Variation in the Emergency Department Prevalence Of Sepsis., C McNevin, Ronald McDowell, A NiShearcaigh, and Abel Wakai

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Supporting general practitioner-based care for poorly controlled type 2 diabetes mellitus (the DECIDE study): feasibility study and protocol for a pilot cluster randomised controlled trial., Mark E. Murphy, Molly Byrne, Fiona Boland, Derek Corrigan, Paddy Gillespie, Tom Fahey, and Susan M. Smith

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Prevalence of potentially inappropriate prescribing in older people in primary care and its association with hospital admission: longitudinal study, Teresa Perez, Frank Moriarty, Emma Wallace, Ronald McDowell, and Patrick Redmond

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Quantifying patient preferences for symptomatic breast clinic referral: a decision analysis study., Aisling Quinlan, Kirsty K. O'Brien, Rose Galvin, Colin Hardy, Ronan McDonnell, Doireann Joyce, Ronald McDowell, Emma Aherne, Claire Keogh, Katriona O'Sullivan, and Tom Fahey

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Does patient self-management education of primary care professionals improve patient outcomes: a systematic review., Andree Rochfort, Sinead Beirne, Gillian Doran, Patricia Patton, Jochen Gensichen, Ilkka Kunnamo, Susan M. Smith, Tina Eriksson, and Claire Collins

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Relationship between self-efficacy, self-care behaviour and glycaemic control among patients with type 2 diabetes mellitus in the Malaysian primary care setting., Zahirah Tharek, Anis Safura Ramli, David L. Whitford, Zaliha Ismail, Maryam Mohd Zulkifli, Siti Khuzaimah Ahmad Sharoni, Asrul A. Shafie, and Thevaraajan Jayaraman

Submissions from 2017

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Intramuscular oxytocin versus intravenous oxytocin to prevent postpartum haemorrhage at vaginal delivery (LabOR trial): study protocol for a randomised controlled trial., Nita Adnan, Fiona Boland, and Deirdre J. Murphy

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The Penicillin for the Emergency Department Outpatient treatment of CELLulitis (PEDOCELL) trial: update to the study protocol and detailed statistical analysis plan (SAP)., Fiona Boland, Michael Quirke, Brenda Gannon, Sinead Plunkett, John Hayden, John McCourt, Ronan O'Sullivan, Joseph Eustace, Conor Deasy, and Abel Wakai

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Diagnosing malignant melanoma in ambulatory care: a systematic review of clinical prediction rules., Emma Harrington, Barbara Clyne, Nieneke Wesseling, Harkiran Sandhu, Laura Armstrong, Holly Bennett, and Tom Fahey

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Supporting prescribing in older people with multimorbidity and significant polypharmacy in primary care (SPPiRE): a cluster randomised controlled trial protocol and pilot., Caroline McCarthy, Barbara Clyne, Derek Corrigan, Fiona Boland, Emma Wallace, Frank Moriarty, Tom Fahey, Carmel Hughes, Paddy Gillespie, and Susan M. Smith

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Potentially inappropriate prescribing and its association with health outcomes in middle-aged people: a prospective cohort study in Ireland., Frank Moriarty, Caitriona Cahir, Kathleen Bennett, Carmel M. Hughes, Rose Anne Kenny, and Tom Fahey

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Improving risk factor management for patients with poorly controlled type 2 diabetes: a systematic review of healthcare interventions in primary care and community settings., Mark E. Murphy, Molly Byrne, Rose Galvin, Fiona Boland, Tom Fahey, and Susan M. Smith

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Development of a complex intervention to promote appropriate prescribing and medication intensification in poorly controlled type 2 diabetes mellitus in Irish general practice., Mark E. Murphy, Molly Byrne, Atieh Zarabzadeh, derek corrigan, Tom Fahey, and Susan M. Smith

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A comparative study: do "clickers" increase student engagement in multidisciplinary clinical microbiology teaching?, Niall T. Stevens, Hélène McDermott, Fiona Boland, Teresa Pawlikowska, and Hilary Humphreys

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External validation of the Vulnerable Elder's Survey for predicting mortality and emergency admission in older community-dwelling people: a prospective cohort study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Impact of Potentially Inappropriate Prescribing on Adverse Drug Events, Health Related Quality of Life and Emergency Hospital Attendance in Older People Attending General Practice: A Prospective Cohort Study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Study protocol for evaluating the implementation and effectiveness of an emergency department longitudinal patient monitoring system using a mixed-methods approach., Marie Ward, Eilish McAuliffe, Abel Wakai, Una Geary, John Browne, Conor Deasy, Michael Schull, Fiona Boland, Fiona McDaid, Eoin Coughlan, and Ronan O'Sullivan

Submissions from 2016

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PIPc study: development of indicators of potentially inappropriate prescribing in children (PIPc) in primary care using a modified Delphi technique., Emma Barry, Kirsty O'Brien, Frank Moriarty, Janine Cooper, Patrick Redmond, Carmel M. Hughes, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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A process evaluation of a cluster randomised trial to reduce potentially inappropriate prescribing in older people in primary care (OPTI-SCRIPT study)., Barbara Clyne, Janine A. Cooper, Carmel M. Hughes, Tom Fahey, Susan M. Smith, and OPTI-SCRIPT study team

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‘Potentially inappropriate or specifically appropriate?’ Qualitative evaluation of general practitioners views on prescribing, polypharmacy and potentially inappropriate prescribing in older people., Barbara Clyne, Janine A. Cooper, Carmel M. Hughes, Tom Fahey, Susan M. Smith, and OPTI-SCRIPT Study Team

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Interventions to Address Potentially Inappropriate Prescribing in Community-Dwelling Older Adults: A Systematic Review of Randomized Controlled Trials., Barbara Clyne, Ciaran Fitzgerald, Aisling Quinlan, Colin Hardy, Rose Galvin, Tom Fahey, and Susan M. Smith

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Sustained effectiveness of a multifaceted intervention to reduce potentially inappropriate prescribing in older patients in primary care (OPTI-SCRIPT study)., Barbara Clyne, Susan M. Smith, Carmel M. Hughes, Fiona Boland, Janine A Cooper, Tom Fahey, and OPTI-SCRIPT study team

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Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria., Janine A. Cooper, Frank Moriarty, Cristín Ryan, Susan M. Smith, Kathleen Bennett, Tom Fahey, Emma Wallace, Caitriona Cahir, David Williams, Mary Teeling, and Carmel M. Hughes

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Training doctors to manage patients with multimorbidity: a systematic review, Cliona Lewis, Emma Wallace, Lorraine Kyne, Walter Cullen, and Susan M. Smith

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What Proportion of Patients Meet the Criteria for Uncomplicated Sepsis in an Irish Emergency Department?, C McNevin, Ronald McDowell, Fidelma Fitzpatrick, Peadar Gilligan, and Abel Wakai

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Scaling up health knowledge at European level requires sharing integrated data: an approach for collection of database specification., Enrica Menditto, Angela Bolufer De Gea, Caitriona Cahir, Alessandra Marengoni, Salvatore Riegler, Giuseppe Fico, Elisio Costa, Alessandro Monaco, Sergio Pecorelli, Luca Pani, and Alexandra Prados-Torres

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Characterizing Potentially Inappropriate Prescribing of Proton Pump Inhibitors in Older People in Primary Care in Ireland from 1997 to 2012., Frank Moriarty, Kathleen Bennett, Caitriona Cahir, and Tom Fahey

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Potentially inappropriate prescribing according to STOPP and START and adverse outcomes in community-dwelling older people: a prospective cohort study., Frank Moriarty, Kathleen Bennett, Caitriona Cahir, Rose Anne Kenny, and Tom Fahey

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GPs' and community pharmacists' opinions on medication management at transitions of care in Ireland., Patrick Redmond, Hailey Carroll, Tamasine Grimes, Rose Galvin, Ronan McDonnell, Fiona Boland, Ronald McDowell, Carmel Hughes, and Tom Fahey

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De novo post-diagnosis statin use, breast cancer-specific and overall mortality in women with stage I-III breast cancer., Amelia Smith, Laura Murphy, Linda Sharp, Darran P. O'Connor, William M. Gallagher, Kathleen Bennett, and Thomas I. Barron

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Comparison of count-based multimorbidity measures in predicting emergency admission and functional decline in older community-dwelling adults: a prospective cohort study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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External validation of the Probability of repeated admission (Pra) risk prediction tool in older community-dwelling people attending general practice: a prospective cohort study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Impact of Potentially Inappropriate Prescribing on Adverse Drug Events, Health Related Quality of Life and Emergency Hospital Attendance in Older People Attending General Practice: A Prospective Cohort Study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Impact analysis studies of clinical prediction rules relevant to primary care: a systematic review., Emma Wallace, Maike JM Uijen, Barbara Clyne, Atieh Zarabzadeh, Claire Keogh, Rose Galvin, Susan M. Smith, and Tom Fahey

Submissions from 2015

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Meta-analysis of the efficacy of a single stage laparoscopic management versus two-stage endoscopic management of symptomatic gallstones with common bile duct stones., Olushola Ajayi, Borislav D. Dimitrov, Mitchel Barry, and Malcolm R. Kell

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Assessing potentially inappropriate prescribing (PIP) and predicting patient outcomes in Ontario's older population: a population-based cohort study applying subsets of the STOPP/START and Beers' criteria in large health administrative databases., Lise M. Bjerre, Timothy Ramsay, Catriona Cahir, Cristín Ryan, Roland Halil, Barbara Farrell, Kednapa Thavorn, Christina Catley, Steven Hawken, Ulrika Gillespie, and Douglas G. Manuel

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Psychostimulant prescribing trends in a paediatric population in Ireland: a national cohort study., Fiona Boland, Rose Galvin, Udo Reulbach, Nicola Motterlini, Dervla Kelly, Kathleen Bennett, and Tom Fahey

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Prevalence of prescribing in pregnancy using the Irish primary care research network: a pilot study., Paul Dillon, Kirsty K. O'Brien, Ronan McDonnell, Erica Donnelly-Swift, Rose Galvin, Adam Roche, Kate Cronin, David R. Walsh, Rowan Schelten, Susan Smith, and Tom Fahey

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A simplified approach to the pooled analysis of calibration of clinical prediction rules for systematic reviews of validation studies., Borislav D. Dimitrov, Nicola Motterlini, and Tom Fahey

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OPTIMAL, an occupational therapy led self-management support programme for people with multimorbidity in primary care: a randomized controlled trial., Jess Garvey, Deirdre Connolly, Fiona Boland, and Susan M. Smith

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A systematic review of the cost of data collection for performance monitoring in hospitals., Cheryl Jones, Brenda Gannon, Abel Wakai, and Ronan O'Sullivan

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Health and use of health services of people who are homeless and at risk of homelessness who receive free primary health care in Dublin., Claire Keogh, Kirsty K. O'Brien, Anthony Hoban, Austin O'Carroll, and Tom Fahey

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International students' experience of a western medical school: a mixed methods study exploring the early years in the context of cultural and social adjustment compared to students from the host country., Alice McGarvey, Ruairi Brugha, Ronán Conroy, Eric Clarke, and Elaine Byrne

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Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people., Frank Moriarty, Kathleen Bennett, Tom Fahey, Rose Anne Kenny, and Caitriona Cahir

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Trends and interaction of polypharmacy and potentially inappropriate prescribing in primary care over 15 years in Ireland: a repeated cross-sectional study., Frank Moriarty, Colin Hardy, Kathleen Bennett, Susan M. Smith, and Tom Fahey

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Six-year follow-up of the SPHERE RCT: secondary prevention of heart disease in general practice., Andrew W. Murphy, M E. Cupples, E Murphy, J Newell, C J. Scarrott, A Vellinga, P Gillespie, M Byrne, C Kearney, and Susan M. Smith

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Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA)., Catriona Murphy, Kathleen Bennett, Tom Fahey, Emer Shelley, Ian Graham, and Rose Anne Kenny

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Antidepressant prescribing in Irish children: secular trends and international comparison in the context of a safety warning., Katriona O'Sullivan, Fiona Boland, Udo Reulbach, Nicola Motterlini, Dervla Kelly, Kathleen Bennett, and Tom Fahey

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Benzodiazepine prescribing in children under 15 years of age receiving free medical care on the General Medical Services scheme in Ireland., Katriona O'Sullivan, Udo Reulbach, Fiona Boland, Nicola Motterlini, Dervla Kelly, Kathleen Bennett, and Tom Fahey

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Prevalence and predictors of initial oral antibiotic treatment failure in adult emergency department patients with cellulitis: a pilot study., Michael Quirke, Fiona Boland, Tom Fahey, Ronan O'Sullivan, Arnold DK Hill, Ian Stiell, and Abel Wakai

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Treatment outcome measures for randomized controlled trials of antibiotic treatment for acute bacterial skin and skin structure infections in the emergency department setting., Michael Quirke and Abel Wakai

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Multimorbidity and functional decline in community-dwelling adults: a systematic review., Aine Ryan, Emma Wallace, Paul O'Hara, and Susan M. Smith

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TElehealth in CHronic disease: mixed-methods study to develop the TECH conceptual model for intervention design and evaluation., Chris Salisbury, Clare Thomas, Alicia O'Cathain, Anne Rogers, Catherine Pope, Lucy Yardley, Sandra Hollinghurst, Tom Fahey, Glyn Lewis, Shirley Large, Louisa Edwards, Alison Rowsell, Julia Segar, Simon Brownsell, and Alan A. Montgomery

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Evidence-based rules from family practice to inform family practice; the learning healthcare system case study on urinary tract infections., Jean K. Soler, Derek Corrigan, Przemyslaw Kazienko, Tomasz Kajdanowicz, Roxana Danger, Marcin Kulisiewicz, and Brendan Delaney

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Secondary analysis of data on comorbidity/multimorbidity: a call for papers., Marjan van den Akker, Jane Gunn, Stewart W. Mercer, Martin Fortin, and Susan M. Smith

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Managing patients with multimorbidity in primary care., Emma Wallace, Chris Salisbury, Bruce Guthrie, Cliona Lewis, Tom Fahey, and Susan M. Smith

Submissions from 2014

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Is the Timed Up and Go test a useful predictor of risk of falls in community dwelling older adults: a systematic review and meta- analysis., Emma Barry, Rose Galvin, Frances Horgan, and Tom Fahey

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Potentially inappropriate prescribing among older people in the United Kingdom., Marie C. Bradley, Nicola Motterlini, Shivani Padmanabhan, Caitriona Cahir, Tim Williams, Tom Fahey, and Carmel M. Hughes

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Locking plate fixation with and without inferomedial screws for proximal humeral fractures: a biomechanical study., Neil G. Burke, Jim Kennedy, Grainne Cousins, David Fitzpatrick, and Hannan Mullett

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Prescriber variation in potentially inappropriate prescribing in older populations in Ireland., Caitriona Cahir, Tom Fahey, Conor Teljeur, and Kathleen Bennett

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Potentially inappropriate prescribing and vulnerability and hospitalization in older community-dwelling patients., Caitriona Cahir, Frank Moriarty, Conor Teljeur, Tom Fahey, and Kathleen Bennett

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Using postal questionnaires to evaluate physical activity and diet behaviour change: case study exploring implications of valid responder characteristics in interpreting intervention outcomes., Judith A. Cole, Paddy Gillespie, Susan M. Smith, Molly Byrne, Andrew W. Murphy, and Margaret E. Cupples

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The development of the PROMPT (PRescribing Optimally in Middle-aged People's Treatments) criteria., Janine A. Cooper, Cristín Ryan, Susan M. Smith, Emma Wallace, Kathleen Bennett, Caitriona Cahir, David Williams, Mary Teeling, Tom Fahey, Carmel M. Hughes, and The PROMPT Steering Group

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Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing., Grainne Cousins, Rose Galvin, Michelle Flood, Mary-Claire Kennedy, Nicola Motterlini, Martin C. Henman, Rose-Anne Kenny, and Tom Fahey

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Retraction of statins article is not in the public interest: better characterisation of benefits and risks is crucial., Tom Fahey and Susan M. Smith

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Long-term risk of stroke after transient ischaemic attack: a hospital-based validation of the ABCD2 rule., Rose Galvin, Penka A. Atanassova, Nicola Motterlini, Tom Fahey, and Borislav D. Dimitrov

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Development and validation of a clinical prediction rule to identify suspected breast cancer: a prospective cohort study., Rose Galvin, Doireann Joyce, Eithne Downey, Fiona Boland, Tom Fahey, and Arnold DK Hill

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Prevalence of potentially inappropriate prescribing and prescribing omissions in older Irish adults: findings from The Irish LongituDinal Study on Ageing study (TILDA)., Rose Galvin, Frank Moriarty, Grainne Cousins, Caitriona Cahir, Nicola Motterlini, Marie Bradley, Carmel M. Hughes, Kathleen Bennett, Susan M. Smith, Tom Fahey, and Rose-Anne Kenny

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The cost of data collection for performance monitoring in hospitals: protocol for a systematic review., Brenda Gannon, Cheryl Jones, Abel Wakai, and Ronan O'Sullivan

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Computer-based clinical decision support for general practitioners., Mark E. Murphy, Tom Fahey, and Susan M. Smith

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RE: Towards realistic and flexible advance care planning., Brendan O'Shea, Geoff King, Catherine McGuinness, and David Smith

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A pilot cross-sectional study of patients presenting with cellulitis to emergency departments., Michael Quirke, Jean Saunders, Ronald O'Sullivan, Hristijan Milenkovski, and Abel Wakai

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Antibiotics for acute bronchitis., Susan M. Smith, Tom Fahey, John Smucny, and Lorne A. Becker

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Enhancing research quality and reporting: why the Journal of Comorbidity is now publishing study protocols, Susan M. Smith, Stewart W. Mercer, Jane Gunn, Marjan van den Akker, and Martin Fortin

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Risk prediction models to predict emergency hospital admission in community-dwelling adults: a systematic review., Emma Wallace, Ellen Stuart, Niall Vaughan, Kathleen Bennett, Tom Fahey, and Susan M. Smith

Submissions from 2013

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Addressing potentially inappropriate prescribing in older patients: development and pilot study of an intervention in primary care (the OPTI-SCRIPT study)., Barbara Clyne, Marie C. Bradley, Carmel M. Hughes, Daniel Clear, Ronan McDonnell, David Williams, Tom Fahey, Susan M. Smith, and OPTI-SCRIPT study team

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Effectiveness of medicines review with web-based pharmaceutical treatment algorithms in reducing potentially inappropriate prescribing in older people in primary care: a cluster randomized trial (OPTI-SCRIPT study protocol)., Barbara Clyne, Marie C. Bradley, Susan M. Smith, Carmel M. Hughes, Nicola Motterlini, Daniel Clear, Ronan McDonnell, David Williams, Tom Fahey, and OPTI-SCRIPT study team

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Do practitioners and friends support patients with coronary heart disease in lifestyle change? a qualitative study., Judith A. Cole, Susan M. Smith, Nigel Hart, and Margaret E. Cupples

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An ontological treatment of clinical prediction rules implementing the Alvarado score., Derek Corrigan, Adel Taweel, Tom Fahey, Theodoras Arvanitis, and Brendan Delaney

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Protocol for a systematic review and individual patient data meta-analysis of prognostic factors of foot ulceration in people with diabetes: the international research collaboration for the prediction of diabetic foot ulcerations (PODUS)., Fay Crawford, Chantelle Anandan, Francesca M. Chappell, Gordon D. Murray, Jacqueline F. Price, Aziz Sheikh, Colin R. Simpson, Martin Maxwell, Gerard P. Stansby, Matthew J. Young, Caroline A. Abbott, Andrew JM Boulton, Edward J. Boyko, Thomas Kastenbauer, Graham P. Leese, Matteo Monami, Matilde Monteiro-Soares, Stephen J. Rith-Najarian, Aristidis Veves, Nikki Coates, William J. Jeffcoate, Nicola Leech, Tom Fahey, and Jayne Tierney

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Improving the external validity of clinical trials: the case of multiple chronic conditions, Martin Fortin and Susan M. Smith

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Prescribing patterns of glucosamine in an older population: a national cohort study., Rose Galvin, Grainne Cousins, Fiona Boland, Nicola Motterlini, Kathleen Bennett, and Tom Fahey

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Recurring themes arising during medical research ethics committee review., Eoin Kelleher, Alice Stanton, Gillian Vale, and David Smith

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Structured sedation programs in the emergency department, hospital and other acute settings: protocol for systematic review of effects and events., Siobhán McCoy, Abel Wakai, Carol Blackburn, Michael Barrett, Adrian Murphy, Maria Brenner, Philip Larkin, Gloria Crispino-O Connell, Savithiri Ratnapalan, and Ronan O Sullivan