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Submissions from 2016

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Treatment of Mycobacterium tuberculosis-Infected Macrophages with Poly(Lactic-Co-Glycolic Acid) Microparticles Drives NFκB and Autophagy Dependent Bacillary Killing., Ciaran Lawlor, Gemma O'Connor, Seonadh O'Leary, Paul J. Gallagher, Sally-Ann Cryan, Joseph Keane, and Mary P. O'Sullivan

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Inhibition of major integrin αVβ3 reduces Staphylococcus aureus attachment to sheared human endothelial cells., C J. McDonnell, C D. Garciarena, R L. Watkin, T M. McHale, A McLoughlin, J Claes, P Verhamme, P M. Cummins, and S W. Kerrigan

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Sharpening nature's tools for efficient tuberculosis control: A review of the potential role and development of host-directed therapies and strategies for targeted respiratory delivery., Gemma O'Connor, Laura E. Gleeson, Aidan Fagan-Murphy, Sally-Ann Cryan, Mary P. O'Sullivan, and Joseph Keane

Submissions from 2015

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Assessing potentially inappropriate prescribing (PIP) and predicting patient outcomes in Ontario's older population: a population-based cohort study applying subsets of the STOPP/START and Beers' criteria in large health administrative databases., Lise M. Bjerre, Timothy Ramsay, Catriona Cahir, Cristín Ryan, Roland Halil, Barbara Farrell, Kednapa Thavorn, Christina Catley, Steven Hawken, Ulrika Gillespie, and Douglas G. Manuel

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Improving appropriate polypharmacy for older people in primary care: selecting components of an evidence-based intervention to target prescribing and dispensing., Cathal A. Cadogan, Cristín Ryan, Jill J. Francis, Gerard J. Gormley, Peter Passmore, Ngaire Kerse, and Carmel M. Hughes

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Combinatorial gene therapy accelerates bone regeneration: non-viral dual delivery of VEGF and BMP2 in a collagen-nanohydroxyapatite scaffold., Caroline M. Curtin, Erica G. Tierney, Kevin McSorley, Sally-Ann Cryan, Garry P. Duffy, and Fergal O'Brien

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Hepatitis C in the era of direct-acting antivirals: real-world costs of untreated chronic hepatitis C; a cross-sectional study., Jennifer A. Kiernan, Suzanne Norris, Aisling O'Leary, Cathal Walsh, Raphael Merriman, D Houlihan, P Aiden McCormick, Susan McKiernan, Colm Bergin, and Michael Barry

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Incorporation of polymeric microparticles into collagen-hydroxyapatite scaffolds for the delivery of a pro-osteogenic peptide for bone tissue engineering, Adolfo López-Noriega, Elaine Quinlan, Nehar Celikkin, and Fergal O'Brien

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Relationship between performance barriers and pharmacist competency towards the implementation of an expanded public health pharmacy role., Amuthaganesh Mathialagan, Preesha Nagalinggam, Saravanabavan Mathialagan, and Brian P. Kirby

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Prevalence and risk factors for modified prescriptions in an Irish community pharmacy., Samuel Obassi, Frank Doyle, and Alan Tinsley

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Generic medicines and generic substitution: contrasting perspectives of stakeholders in Ireland., Aisling O'Leary, Cara Usher, Matthew Lynch, M Hall, L Hemeryk, Susan Spillane, Paul Gallagher, and Michael Barry

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Respiratory Tissue Engineering: Current Status and Opportunities for the Future., Cian O'Leary, Jennifer L. Gilbert, Shirley O'Dea, Fergal O'Brien, and Sally-Ann Cryan

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Development of collagen-hydroxyapatite scaffolds incorporating PLGA and alginate microparticles for the controlled delivery of rhBMP-2 for bone tissue engineering., Elaine Quinlan, Adolfo López-Noriega, Emmet Thompson, Helena M. Kelly, Sally-Ann Cryan, and Fergal O'Brien

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Development of a gene-activated scaffold platform for tissue engineering applications using chitosan-pDNA nanoparticles on collagen-based scaffolds., Rosanne M. Raftery, Erica G. Tierney, Caroline M. Curtin, Sally-Ann Cryan, and Fergal O'Brien

Submissions from 2014

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Effect of the N-methyl-D-aspartate NR2B subunit antagonist ifenprodil on precursor cell proliferation in the hippocampus., Eva C. Bunk, Hans-Georg König, Jochen HM Prehn, and Brian P. Kirby

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2009 A/H1N1 influenza vaccination in pregnancy: uptake and pregnancy outcomes - a historical cohort study., Brian J Cleary, Úna Rice, Maeve Eogan, Nehad Metwally, and Fionnuala McAuliffe

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Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing., Grainne Cousins, Rose Galvin, Michelle Flood, Mary-Claire Kennedy, Nicola Motterlini, Martin C. Henman, Rose-Anne Kenny, and Tom Fahey

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Early-stage development of novel cyclodextrin-siRNA nanocomplexes allows for successful postnebulization transfection of bronchial epithelial cells., Alan Hibbitts, A M. O'Mahony, E Forde, L Nolan, J Ogier, S Desgranges, R Darcy, R MacLoughlin, C M. O'Driscoll, and Sally-Ann Cryan

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High-throughput methods for screening liposome-macrophage cell interaction., Ciara Kelly, Ciaran Lawlor, Colin Burke, James W. Barlow, Joanne M. Ramsey, Caroline Jefferies, and Sally-Ann Cryan

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Fast disintegrating crystalline solid dispersions of simvastatin for incorporation into orodispersible tablets, Ritesh M. Pabari, Asha Jamil, John G. Kelly, and Zebunnissa Ramtoola

Submissions from 2013

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Prescribing patterns of glucosamine in an older population: a national cohort study., Rose Galvin, Grainne Cousins, Fiona Boland, Nicola Motterlini, Kathleen Bennett, and Tom Fahey

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Platelet-bacterial interactions in the pathogenesis of infective endocarditis. Part II: The Staphylococcus, Steven W. Kerrigan

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Comparative evaluation of novel biodegradable nanoparticles for the drug targeting to breast cancer cells., Clara Mattu, Ritesh Pabari, M Boffito, S Sartori, G Ciardelli, and Zeibun Ramtoola

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Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes - a prospective cohort study., Deirdre J. Murphy, Aoife Mullally, Brian J. Cleary, Tom Fahey, and Joe Barry

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Physical and structural stability of the monoclonal antibody, trastuzumab (Herceptin®), intravenous solutions., Ritesh M. Pabari, Benedict Ryan, Wazir Ahmad, and Zebunnissa Ramtoola

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Chitosan for gene delivery and orthopedic tissue engineering applications., Rosanne Raftery, Fergal O'Brien, and Sally-Ann Cryan

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'Smart' non-viral delivery systems for targeted delivery of RNAi to the lungs., Joanne M. Ramsey, Alan Hibbitts, James Barlow, Neeraj Sivadas, and Sally-Ann Cryan

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Medial prefrontal cortex lesions in mice do not impair effort-based decision making., Christine Solinsky and Brian P. Kirby

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Platelet-bacterial interactions in the pathogenesis of infective endocarditis. Part I: The Streptococcus, Dorothea Tilley and Steven W. Kerrigan

Submissions from 2012

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Medical Students' Knowledge, Perceptions, and Interest in Complementary and Alternative Medicine., Kah P. Loh, Hatem Ghorab, Eric Clarke, Ronán Conroy, and James Barlow

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Preparation and Characterization of Simvastatin Loaded PLGA Microparticles forTissue Engineering Applications, Vijay K. Nandagiri, Clara Muttu, Jacqueline Daly, Ziebun Ramtoola, Gianluca Ciardelli, and Franco M. Montevecchi

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Stability of an alternative extemporaneous captopril fast-dispersing tablet formulation versus an extemporaneous oral liquid formulation., Ritesh M. Pabari, Claire McDermott, James Barlow, and Zebunnissa Ramtoola

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Application of face centred central composite design to optimise compression force and tablet diameter for the formulation of mechanically strong and fast disintegrating orodispersible tablets., Ritesh M. Pabari and Zebunnissa Ramtoola

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Investigation of a novel 3-fluid nozzle spray drying technology for the engineering of multifunctional layered microparticles., Ritesh M. Pabari, Tara Sunderland, and Zebunnissa Ramtoola

Submissions from 2011

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In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens., Stephane Desgranges, Florie Le Prieult, Alan Daly, Marian Brennan, Dilip K. Rai, Anusha P. Subasinghage, Chandralal M. Hewage, Sally-Ann Cryan, Catherine M. Greene, Noel G. McElvaney, Timothy P. Smyth, Deirdre Fitzgerald-Hughes, Hilary Humphreys, and Marc Devocelle

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The effect of liposome encapsulation on the pharmacokinetics of recombinant secretory leukocyte protease inhibitor (rSLPI) therapy after local delivery to a guinea pig asthma model., Aileen Gibbons, Danielle Padilla-Carlin, Ciara Kelly, Anthony J. Hickey, Clifford Taggart, Noel G. McElvaney, and Sally-Ann Cryan

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Screening of siRNA Nanoparticles for Delivery to Airway Epithelial Cells Using High Content Analysis, Alan Hibbitts, Nora Lieggi, Olive McCabe, Warren Thomas, James Barlow, Fiona O'Brien, and Sally-Ann Cryan

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Targeted liposomal drug delivery to monocytes and macrophages., Ciara Kelly, Caroline Jefferies, and Sally-Ann Cryan

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Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland., Aoife Mullally, Brian J. Cleary, Joe Barry, Tom P. Fahey, and Deirdre J. Murphy

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Incorporation of PLGA nanoparticles into porous chitosan-gelatin scaffolds: influence on the physical properties and cell behavior., Vijay Kumar Nandagiri, Piergiorgio Gentile, Valeria Chiono, Chiara Tonda-Turo, Amos Matsiko, Zeibun Ramtoola, Franco Maria Montevecchi, and Gianluca Ciardelli

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Effect of Microencapsulation Sheer Stress on the Structural Integrity and Biological Activity of a Model Monoclonal Antibody, Trastuzumab, Ritesh M. Pabari, Benedict Ryan, Catherine McCarthy, and Zebunnissa Ramtoola

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The effects of excipients and particle engineering on the biophysical stability and aerosol performance of parathyroid hormone (1-34) prepared as a dry powder for inhalation., Sunday A. Shoyele, Neeraj Sivadas, and Sally-Ann Cryan

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Inhalable, bioresponsive microparticles for targeted drug delivery in the lungs., Neeraj Sivadas and Sally-Ann Cryan

Submissions from 2010

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BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus., Eva C. Bunk, Hans-Georg König, Tytus Bernas, Tobias Engel, David C. Henshall, Brian P. Kirby, and Jochen HM Prehn

Submissions from 2008

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A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins., Neeraj Sivadas, Desmond O'Rourke, Aoife Tobin, Zeibun Ramtoola, John G. Kelly, Anthony J. Hickey, and Sally-Ann Cryan

Submissions from 2007

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In vivo animal models for drug delivery across the lung mucosal barrier., Sally-Ann Cryan, Neeraj Sivadas, and Lucila Garcia-Contreras