Peer Reviewed

1

Document Type

Article

Publication Date

2-2017

Keywords

Chronic obstructive pulmonary disease (COPD), adherence, inhaler, electronic monitor, construct validity, predictive validity

Funder/Sponsor

Royal College of Surgeons in Ireland Research Institute.

Comments

This is an Accepted Manuscript of an article published by Taylor & Francis in Psychology & Health on 2017, available online: http://www.tandfonline.com/ http://dx.doi.org/10.1080/08870446.2017.1290243

Abstract

Objective: To compare the Inhaler Compliance AssessmentTM (INCATM), a novel audio-recording device objectively measuring timing and proficiency of inhaler use, against established adherence measures, and explore its discriminant and predictive validity.

Design: Prospective observational study; 184 chronic obstructive pulmonary disease (COPD) patients used an INCATM-enabled salmeterol/fluticasone inhaler for one-month post-hospital discharge.

Main outcome measures: INCATM (Attempted, Attempted Interval, Actual) adherence correlated with Doses Used Rate, self-reported adherence and prescription refill for concurrent validity. Discriminant validity for reason for admission, cognition and lung function; predictive validity for health status and quality-of-life.

Results: Rates of Attempted, Attempted Interval and Actual adherence were 59, 47 and 23%, respectively. Only 7% of participants had Actual adherence >80%. INCATM variables significantly correlated with Doses Used Rate but not with self-report; Attempted and Attempted Interval were weakly associated with prescription refill. Higher cognitive and lung functioning groups had better INCATM adherence. Attempted and Attempted Interval predicted health status, while Doses Used Rate predicted quality-of-life.

Conclusion: INCATM did not strongly correlate with self-report or prescription refill data. Discriminant and predictive validity demonstrated by INCATM suggests the potential utility of the INCATM as a method to identify intentional and unintentional adherence to inhaled medication and facilitate targeted intervention.

Disciplines

Psychology

Citation

Moran C, Doyle F, Sulaiman I, Bennett K, Green G, Molloy GJ, Reilly RB, Costello RW, Mellon L. The INCATM (Inhaler Compliance AssessmentTM): A comparison with established measures of adherence. Psychology & Health. 2017;28:1-21

PubMed ID

28276739

DOI Link

http://dx.doi.org/10.1080/08870446.2017.1290243

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This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.

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