Adult, cancer immunotherapy, case report, computer assisted tomography, drug dose reduction, drug megadose, dysphagia, esophagoscopy, esophagus biopsy, esophagus cancer, esophagus resection, follow up, gastroesophageal reflux, histopathology, human tissue, lymph node metastasis, lymphadenectomy, male, mediastinum lymph node, melanoma, positron emission tomography, weight reduction
Primary malignant melanoma of the oesophagus is a rare neoplasm comprising less than 0.2% of all primary oesophageal neoplasms. There are fewer than 250 reported cases in worldwide literature. Several reports suggest that it has a mean survival rate of 2.2% at 5 years and a median survival rate of 10 months. A 48 year old male presented to our surgical service complaining of a three month history of progressively worsening dysphagia with associated regurgitation and unintentional weight loss of 14 kg. There was no prior history of cutaneous or ocular melanoma. He was treated with a combination of subtotal oesophageal resection and immunomodulatory therapy. We present herein a case of primary malignant melanoma of the oesophagus including the associated clinical, pathological and radiological findings.
Medical Pathology | Pathology
Kelly J, Leader M, Broe P. Primary malignant melanoma of the oesophagus: a case report. Journal of Medical Case Reports. 2007;1:50.