CD40 Ligand, Continuous Positive Airway Pressure, Humans, Platelet Activation, Sleep Apnea, Obstructive
Obstructive sleep apnoea (OSA) is a complex condition associated with a number of cardiovascular sequelae including hypertension (both systemic and pulmonary), congestive heart failure, arrhythmias, myocardial infarction and stroke [1-6]. However, the recent American Heart Association/American College of Cardiology scientific statement on sleep apnoea suggests that there is a paucity of data for a causal role of OSA in cardiovascular disease  which underlines the importance of studies such as that of Akinnusi and co-workers in this edition of Respiration that are aimed at understanding the pathophysiology of OSA.
Cox D, Bradford A. Continuous positive airway pressure and platelet activation in obstructive sleep apnoea. Respiration 2009;77:18-20.