Peer Reviewed

1

Document Type

Article

Publication Date

2011

Keywords

ABCD2, risk prediction, stroke, TIA

Comments

This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Family Practice following peer review. The definitive publisher-authenticated version Galvin R, Geraghty C, Motterlini N, Dimitrov BD, Fahey T. Prognostic value of the ABCD2 clinical prediction rule: a systematic review and meta-analysis. Family Practice. 2010;0:1-11 is available online at: http://fampra.oxfordjournals.org/content/early/2011/04/11/fampra.cmr008.long

Abstract

Purpose: The ABCD2 clinical prediction rule (CPR) is designed to predict early risk of stroke after transient ischaemic attack (TIA). The purpose of this systematic review with meta-analysis is to determine the predictive value of the ABCD2 at 7 and 90 days across three strata of risk. Methods: A systematic literature search was conducted to identify studies that validated the ABCD2. The derived rule was used as a predictive model and applied to subsequent validation studies. Comparisons were made between observed and predicted number of strokes stratified by risk group, low (0-3 points), moderate (4-5 points) and high (6-7 points). Pooled results are presented as risk ratios (RRs) with 95% confidence intervals, in terms of over-prediction (RR>1) or under-prediction (RR0.05). Conclusion: The ABCD2 is a useful CPR, particularly in relation to 7 day risk of stroke.

Disciplines

Medicine and Health Sciences

Citation

Galvin R, Geraghty C, Motterlini N, Dimitrov BD, Fahey T. Prognostic value of the ABCD2 clinical prediction rule: a systematic review and meta-analysis. Family Practice. 2010;0:1-11.

PubMed ID

21486940

DOI Link

10.1093/fampra/cmr008

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