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Submissions from 2017

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The Penicillin for the Emergency Department Outpatient treatment of CELLulitis (PEDOCELL) trial: update to the study protocol and detailed statistical analysis plan (SAP)., Fiona Boland, Michael Quirke, Brenda Gannon, Sinead Plunkett, John Hayden, John McCourt, Ronan O'Sullivan, Joseph Eustace, Conor Deasy, and Abel Wakai

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Diagnosing malignant melanoma in ambulatory care: a systematic review of clinical prediction rules., Emma Harrington, Barbara Clyne, Nieneke Wesseling, Harkiran Sandhu, Laura Armstrong, Holly Bennett, and Tom Fahey

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Supporting prescribing in older people with multimorbidity and significant polypharmacy in primary care (SPPiRE): a cluster randomised controlled trial protocol and pilot., Caroline McCarthy, Barbara Clyne, Derek Corrigan, Fiona Boland, Emma Wallace, Frank Moriarty, Tom Fahey, Carmel Hughes, Paddy Gillespie, and Susan M. Smith

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A comparative study: do "clickers" increase student engagement in multidisciplinary clinical microbiology teaching?, Niall T. Stevens, Hélène McDermott, Fiona Boland, Teresa Pawlikowska, and Hilary Humphreys

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External validation of the Vulnerable Elder's Survey for predicting mortality and emergency admission in older community-dwelling people: a prospective cohort study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Impact of Potentially Inappropriate Prescribing on Adverse Drug Events, Health Related Quality of Life and Emergency Hospital Attendance in Older People Attending General Practice: A Prospective Cohort Study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Study protocol for evaluating the implementation and effectiveness of an emergency department longitudinal patient monitoring system using a mixed-methods approach., Marie Ward, Eilish McAuliffe, Abel Wakai, Una Geary, John Browne, Conor Deasy, Michael Schull, Fiona Boland, Fiona McDaid, Eoin Coughlan, and Ronan O'Sullivan

Submissions from 2016

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PIPc study: development of indicators of potentially inappropriate prescribing in children (PIPc) in primary care using a modified Delphi technique., Emma Barry, Kirsty O'Brien, Frank Moriarty, Janine Cooper, Patrick Redmond, Carmel M. Hughes, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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A process evaluation of a cluster randomised trial to reduce potentially inappropriate prescribing in older people in primary care (OPTI-SCRIPT study)., Barbara Clyne, Janine A. Cooper, Carmel M. Hughes, Tom Fahey, Susan M. Smith, and OPTI-SCRIPT study team

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‘Potentially inappropriate or specifically appropriate?’ Qualitative evaluation of general practitioners views on prescribing, polypharmacy and potentially inappropriate prescribing in older people., Barbara Clyne, Janine A. Cooper, Carmel M. Hughes, Tom Fahey, Susan M. Smith, and OPTI-SCRIPT Study Team

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Interventions to Address Potentially Inappropriate Prescribing in Community-Dwelling Older Adults: A Systematic Review of Randomized Controlled Trials., Barbara Clyne, Ciaran Fitzgerald, Aisling Quinlan, Colin Hardy, Rose Galvin, Tom Fahey, and Susan M. Smith

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Sustained effectiveness of a multifaceted intervention to reduce potentially inappropriate prescribing in older patients in primary care (OPTI-SCRIPT study)., Barbara Clyne, Susan M. Smith, Carmel M. Hughes, Fiona Boland, Janine A Cooper, Tom Fahey, and OPTI-SCRIPT study team

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Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria., Janine A. Cooper, Frank Moriarty, Cristín Ryan, Susan M. Smith, Kathleen Bennett, Tom Fahey, Emma Wallace, Caitriona Cahir, David Williams, Mary Teeling, and Carmel M. Hughes

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What Proportion of Patients Meet the Criteria for Uncomplicated Sepsis in an Irish Emergency Department?, C McNevin, Ronald McDowell, Fidelma Fitzpatrick, Peadar Gilligan, and Abel Wakai

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Scaling up health knowledge at European level requires sharing integrated data: an approach for collection of database specification., Enrica Menditto, Angela Bolufer De Gea, Caitriona Cahir, Alessandra Marengoni, Salvatore Riegler, Giuseppe Fico, Elisio Costa, Alessandro Monaco, Sergio Pecorelli, Luca Pani, and Alexandra Prados-Torres

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Characterizing Potentially Inappropriate Prescribing of Proton Pump Inhibitors in Older People in Primary Care in Ireland from 1997 to 2012., Frank Moriarty, Kathleen Bennett, Caitriona Cahir, and Tom Fahey

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Potentially inappropriate prescribing according to STOPP and START and adverse outcomes in community-dwelling older people: a prospective cohort study., Frank Moriarty, Kathleen Bennett, Caitriona Cahir, Rose Anne Kenny, and Tom Fahey

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GPs' and community pharmacists' opinions on medication management at transitions of care in Ireland., Patrick Redmond, Hailey Carroll, Tamasine Grimes, Rose Galvin, Ronan McDonnell, Fiona Boland, Ronald McDowell, Carmel Hughes, and Tom Fahey

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De novo post-diagnosis statin use, breast cancer-specific and overall mortality in women with stage I-III breast cancer., Amelia Smith, Laura Murphy, Linda Sharp, Darran O'Connor, William M. Gallagher, Kathleen Bennett, and Thomas I. Barron

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Comparison of count-based multimorbidity measures in predicting emergency admission and functional decline in older community-dwelling adults: a prospective cohort study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Impact of Potentially Inappropriate Prescribing on Adverse Drug Events, Health Related Quality of Life and Emergency Hospital Attendance in Older People Attending General Practice: A Prospective Cohort Study., Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, and Susan M. Smith

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Impact analysis studies of clinical prediction rules relevant to primary care: a systematic review., Emma Wallace, Maike JM Uijen, Barbara Clyne, Atieh Zarabzadeh, Claire Keogh, Rose Galvin, Susan M. Smith, and Tom Fahey

Submissions from 2015

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Meta-analysis of the efficacy of a single stage laparoscopic management versus two-stage endoscopic management of symptomatic gallstones with common bile duct stones., Olushola Ajayi, Borislav D. Dimitrov, Mitchel Barry, and Malcolm R. Kell

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Assessing potentially inappropriate prescribing (PIP) and predicting patient outcomes in Ontario's older population: a population-based cohort study applying subsets of the STOPP/START and Beers' criteria in large health administrative databases., Lise M. Bjerre, Timothy Ramsay, Catriona Cahir, Cristín Ryan, Roland Halil, Barbara Farrell, Kednapa Thavorn, Christina Catley, Steven Hawken, Ulrika Gillespie, and Douglas G. Manuel

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Psychostimulant prescribing trends in a paediatric population in Ireland: a national cohort study., Fiona Boland, Rose Galvin, Udo Reulbach, Nicola Motterlini, Dervla Kelly, Kathleen Bennett, and Tom Fahey

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Prevalence of prescribing in pregnancy using the Irish primary care research network: a pilot study., Paul Dillon, Kirsty K. O'Brien, Ronan McDonnell, Erica Donnelly-Swift, Rose Galvin, Adam Roche, Kate Cronin, David R. Walsh, Rowan Schelten, Susan Smith, and Tom Fahey

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A simplified approach to the pooled analysis of calibration of clinical prediction rules for systematic reviews of validation studies., Borislav D. Dimitrov, Nicola Motterlini, and Tom Fahey

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OPTIMAL, an occupational therapy led self-management support programme for people with multimorbidity in primary care: a randomized controlled trial., Jess Garvey, Deirdre Connolly, Fiona Boland, and Susan M. Smith

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A systematic review of the cost of data collection for performance monitoring in hospitals., Cheryl Jones, Brenda Gannon, Abel Wakai, and Ronan O'Sullivan

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Health and use of health services of people who are homeless and at risk of homelessness who receive free primary health care in Dublin., Claire Keogh, Kirsty K. O'Brien, Anthony Hoban, Austin O'Carroll, and Tom Fahey

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International students' experience of a western medical school: a mixed methods study exploring the early years in the context of cultural and social adjustment compared to students from the host country., Alice McGarvey, Ruairi Brugha, Ronán Conroy, Eric Clarke, and Elaine Byrne

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Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people., Frank Moriarty, Kathleen Bennett, Tom Fahey, Rose Anne Kenny, and Caitriona Cahir

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Trends and interaction of polypharmacy and potentially inappropriate prescribing in primary care over 15 years in Ireland: a repeated cross-sectional study., Frank Moriarty, Colin Hardy, Kathleen Bennett, Susan M. Smith, and Tom Fahey

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Six-year follow-up of the SPHERE RCT: secondary prevention of heart disease in general practice., Andrew W. Murphy, M E. Cupples, E Murphy, J Newell, C J. Scarrott, A Vellinga, P Gillespie, M Byrne, C Kearney, and Susan M. Smith

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Antidepressant prescribing in Irish children: secular trends and international comparison in the context of a safety warning., Katriona O'Sullivan, Fiona Boland, Udo Reulbach, Nicola Motterlini, Dervla Kelly, Kathleen Bennett, and Tom Fahey

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Prevalence and predictors of initial oral antibiotic treatment failure in adult emergency department patients with cellulitis: a pilot study., Michael Quirke, Fiona Boland, Tom Fahey, Ronan O'Sullivan, Arnold DK Hill, Ian Stiell, and Abel Wakai

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Treatment outcome measures for randomized controlled trials of antibiotic treatment for acute bacterial skin and skin structure infections in the emergency department setting., Michael Quirke and Abel Wakai

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Multimorbidity and functional decline in community-dwelling adults: a systematic review., Aine Ryan, Emma Wallace, Paul O'Hara, and Susan M. Smith

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Evidence-based rules from family practice to inform family practice; the learning healthcare system case study on urinary tract infections., Jean K. Soler, Derek Corrigan, Przemyslaw Kazienko, Tomasz Kajdanowicz, Roxana Danger, Marcin Kulisiewicz, and Brendan Delaney

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Secondary analysis of data on comorbidity/multimorbidity: a call for papers., Marjan van den Akker, Jane Gunn, Stewart W. Mercer, Martin Fortin, and Susan M. Smith

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Managing patients with multimorbidity in primary care., Emma Wallace, Chris Salisbury, Bruce Guthrie, Cliona Lewis, Tom Fahey, and Susan M. Smith

Submissions from 2014

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Is the Timed Up and Go test a useful predictor of risk of falls in community dwelling older adults: a systematic review and meta- analysis., Emma Barry, Rose Galvin, Frances Horgan, and Tom Fahey

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Potentially inappropriate prescribing among older people in the United Kingdom., Marie C. Bradley, Nicola Motterlini, Shivani Padmanabhan, Caitriona Cahir, Tim Williams, Tom Fahey, and Carmel M. Hughes

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Locking plate fixation with and without inferomedial screws for proximal humeral fractures: a biomechanical study., Neil G. Burke, Jim Kennedy, Grainne Cousins, David Fitzpatrick, and Hannan Mullett

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Prescriber variation in potentially inappropriate prescribing in older populations in Ireland., Caitriona Cahir, Tom Fahey, Conor Teljeur, and Kathleen Bennett

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Using postal questionnaires to evaluate physical activity and diet behaviour change: case study exploring implications of valid responder characteristics in interpreting intervention outcomes., Judith A. Cole, Paddy Gillespie, Susan M. Smith, Molly Byrne, Andrew W. Murphy, and Margaret E. Cupples

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The development of the PROMPT (PRescribing Optimally in Middle-aged People's Treatments) criteria., Janine A. Cooper, Cristín Ryan, Susan M. Smith, Emma Wallace, Kathleen Bennett, Caitriona Cahir, David Williams, Mary Teeling, Tom Fahey, Carmel M. Hughes, and The PROMPT Steering Group

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Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing., Grainne Cousins, Rose Galvin, Michelle Flood, Mary-Claire Kennedy, Nicola Motterlini, Martin C. Henman, Rose-Anne Kenny, and Tom Fahey

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Retraction of statins article is not in the public interest: better characterisation of benefits and risks is crucial., Tom Fahey and Susan M. Smith

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Long-term risk of stroke after transient ischaemic attack: a hospital-based validation of the ABCD2 rule., Rose Galvin, Penka A. Atanassova, Nicola Motterlini, Tom Fahey, and Borislav D. Dimitrov

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Development and validation of a clinical prediction rule to identify suspected breast cancer: a prospective cohort study., Rose Galvin, Doireann Joyce, Eithne Downey, Fiona Boland, Tom Fahey, and Arnold DK Hill

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Prevalence of potentially inappropriate prescribing and prescribing omissions in older Irish adults: findings from The Irish LongituDinal Study on Ageing study (TILDA)., Rose Galvin, Frank Moriarty, Grainne Cousins, Caitriona Cahir, Nicola Motterlini, Marie Bradley, Carmel M. Hughes, Kathleen Bennett, Susan M. Smith, Tom Fahey, and Rose-Anne Kenny

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The cost of data collection for performance monitoring in hospitals: protocol for a systematic review., Brenda Gannon, Cheryl Jones, Abel Wakai, and Ronan O'Sullivan

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Computer-based clinical decision support for general practitioners., Mark E. Murphy, Tom Fahey, and Susan M. Smith

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RE: Towards realistic and flexible advance care planning., Brendan O'Shea, Geoff King, Catherine McGuinness, and David Smith

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A pilot cross-sectional study of patients presenting with cellulitis to emergency departments., Michael Quirke, Jean Saunders, Ronald O'Sullivan, Hristijan Milenkovski, and Abel Wakai

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Antibiotics for acute bronchitis., Susan M. Smith, Tom Fahey, John Smucny, and Lorne A. Becker

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Enhancing research quality and reporting: why the Journal of Comorbidity is now publishing study protocols, Susan M. Smith, Stewart W. Mercer, Jane Gunn, Marjan van den Akker, and Martin Fortin

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Risk prediction models to predict emergency hospital admission in community-dwelling adults: a systematic review., Emma Wallace, Ellen Stuart, Niall Vaughan, Kathleen Bennett, Tom Fahey, and Susan M. Smith

Submissions from 2013

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Addressing potentially inappropriate prescribing in older patients: development and pilot study of an intervention in primary care (the OPTI-SCRIPT study)., Barbara Clyne, Marie C. Bradley, Carmel M. Hughes, Daniel Clear, Ronan McDonnell, David Williams, Tom Fahey, Susan M. Smith, and OPTI-SCRIPT study team

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Effectiveness of medicines review with web-based pharmaceutical treatment algorithms in reducing potentially inappropriate prescribing in older people in primary care: a cluster randomized trial (OPTI-SCRIPT study protocol)., Barbara Clyne, Marie C. Bradley, Susan M. Smith, Carmel M. Hughes, Nicola Motterlini, Daniel Clear, Ronan McDonnell, David Williams, Tom Fahey, and OPTI-SCRIPT study team

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Do practitioners and friends support patients with coronary heart disease in lifestyle change? a qualitative study., Judith A. Cole, Susan M. Smith, Nigel Hart, and Margaret E. Cupples

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An ontological treatment of clinical prediction rules implementing the Alvarado score., Derek Corrigan, Adel Taweel, Tom Fahey, Theodoras Arvanitis, and Brendan Delaney

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Protocol for a systematic review and individual patient data meta-analysis of prognostic factors of foot ulceration in people with diabetes: the international research collaboration for the prediction of diabetic foot ulcerations (PODUS)., Fay Crawford, Chantelle Anandan, Francesca M. Chappell, Gordon D. Murray, Jacqueline F. Price, Aziz Sheikh, Colin R. Simpson, Martin Maxwell, Gerard P. Stansby, Matthew J. Young, Caroline A. Abbott, Andrew JM Boulton, Edward J. Boyko, Thomas Kastenbauer, Graham P. Leese, Matteo Monami, Matilde Monteiro-Soares, Stephen J. Rith-Najarian, Aristidis Veves, Nikki Coates, William J. Jeffcoate, Nicola Leech, Tom Fahey, and Jayne Tierney

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Improving the external validity of clinical trials: the case of multiple chronic conditions, Martin Fortin and Susan M. Smith

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Prescribing patterns of glucosamine in an older population: a national cohort study., Rose Galvin, Grainne Cousins, Fiona Boland, Nicola Motterlini, Kathleen Bennett, and Tom Fahey

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Recurring themes arising during medical research ethics committee review., Eoin Kelleher, Alice Stanton, Gillian Vale, and David Smith

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Structured sedation programs in the emergency department, hospital and other acute settings: protocol for systematic review of effects and events., Siobhán McCoy, Abel Wakai, Carol Blackburn, Michael Barrett, Adrian Murphy, Maria Brenner, Philip Larkin, Gloria Crispino-O Connell, Savithiri Ratnapalan, and Ronan O Sullivan

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Effectiveness of systematic screening for the detection of atrial fibrillation., Patrick S. Moran, Martin J. Flattery, Conor Teljeur, Mairin Ryan, and Susan M. Smith

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Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes - a prospective cohort study., Deirdre J. Murphy, Aoife Mullally, Brian J. Cleary, Tom Fahey, and Joe Barry

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Oral flucloxacillin and phenoxymethylpenicillin versus flucloxacillin alone for the emergency department outpatient treatment of cellulitis: study protocol for a randomised controlled trial., Michael Quirke, Abel Wakai, Peadar Gilligan, and Ronan O'Sullivan

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Skills mix: future health policy and workforce planning in primary care., Patrick Redmond

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How to design and evaluate interventions to improve outcomes for patients with multimorbidity, Susan M. Smith, Elizabeth Bayliss, Stewart Mercer, Jane Gunn, Moogens Vestergaard, Sally Wyke, Chris Salisbury, and Martin Fortin

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The epidemiology of malpractice claims in primary care: a systematic review., Emma Wallace, J Lowry, Susan M. Smith, and Tom Fahey

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Patient generated "frequently asked questions": identifying informational needs in a RCT of peer support in type 2 diabetes., David L. Whitford, Gillian Paul, and Susan M. Smith

Submissions from 2012

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Cerebral Venous Sinus Thrombosis - Diagnostic Strategies and Prognostic Models: A Review, Penka A. Atanassova, Radka I. Massaldjieva, Nedka T. Chalakova, and Borislav D. Dimitrov

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Intranasal fentanyl versus intravenous morphine in the emergency department treatment of severe painful sickle cell crises in children: study protocol for a randomised controlled trial., Michael J. Barrett, John Cronin, Adrian Murphy, Siobhan McCoy, John Hayden, SinéadNic an Fhailí, Tim Grant, Abel Wakai, Corrina McMahon, Sean Walsh, and Ronan O'Sullivan

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Diagnostic accuracy of the STRATIFY clinical prediction rule for falls: A systematic review and meta-analysis., Jennifer Billington, Tom Fahey, and Rose Galvin

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Proton pump inhibitors: potential cost reductions by applying prescribing guidelines., Caitriona Cahir, Tom Fahey, Lesley Tilson, Conor Teljeur, and Kathleen Bennett

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Single dose oral dexamethasone versus multi-dose prednisolone in the treatment of acute exacerbations of asthma in children who attend the emergency department: study protocol for a randomized controlled trial., John Cronin, Una Kennedy, Siobhan McCoy, SinéadNic an Fhailí, Gloria Crispino-O'Connell, John Hayden, Abel Wakai, Sean Walsh, and Ronan O'Sullivan

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Behavioural and cognitive-behavioural group-based parenting programmes for early-onset conduct problems in children aged 3 to 12 years., Mairead Furlong, Sinead McGilloway, Tracey Bywater, Judy Hutchings, Susan M. Smith, and Michael Donnelly

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Interventions for improving outcomes in patients with multimorbidity in primary care and community settings., Susan M. Smith, Hassan Soubhi, Martin Fortin, Catherine Hudon, and Tom O'Dowd

Submissions from 2011

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Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score., Jolien Aalbers, Kirsty K. O'Brien, Wai-Sun Chan, Gavin A. Falk, Conor Teljeur, Borislav D. Dimitrov, and Tom Fahey

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Outcome of periacetabular osteotomy for the management of acetabular dysplasia: experience in an academic centre., Neil GM Burke, Brian M. Devitt, Joseph F. Baker, Joseph S. Butler, Grainne Cousins, Damian McCormack, and John M. O'Byrne

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Systematic Review of the Effect of Diet and Exercise Lifestyle Interventions in the Secondary Prevention of Coronary Heart Disease, Judith Cole, Susan M. Smith, Nigel Harte, and Margaret E. Cupples

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Diagnostic accuracy of the ID-Migraine: a systematic review., Grainne Cousins, Samira Hijazze, Floris A. Van de Laar, and Tom Fahey

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Risk of drug related mortality during periods of transition in methadone maintenance treatment: a cohort study, Grainne Cousins, Conor Teljeur, Nicola Motterlini, Colin McCown, Borislav D. Dimitrov, and Tom Fahey

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Prognostic value of the ABCD2 clinical prediction rule: a systematic review and meta-analysis, Rose Galvin, Colm Geraghty, Nicola Motterlini, Borislav D. Dimitrov, and Tom Fahey

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Validation of the CHADS2 clinical prediction rule to predict ischaemic stroke. A systematic review and meta-analysis., Claire Keogh, Emma Wallace, Ciara Dillon, Borislav D. Dimitrov, and Tom Fahey

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Optimized retrieval of primary care clinical prediction rules from MEDLINE to establish a Web-based register., Claire Keogh, Emma Wallace, Kirsty K. O'Brien, Paul J. Murphy, Conor Teljeur, Brid McGrath, Susan M. Smith, Niall Doherty, Borislav D. Dimitrov, and Tom Fahey

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Preventing infection in general surgery: improvements through education of surgeons by surgeons., Seamus M. McHugh, Mark A. Corrigan, Borislav D. Dimitrov, Seamus Cowman, Sean Tierney, Arnold DK Hill, and Hilary Humphreys

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Role of patient awareness in prevention of peripheral vascular catheter-related bloodstream infection., Seamus M. McHugh, Mark A. Corrigan, Borislav D. Dimitrov, Margaret Morris-Downes, Fidelma Fitzpatrick, Seamus Cowman, Sean Tierney, Arnold DK Hill, and Hilary Humphreys

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High concentrations of pepsin in bronchoalveolar lavage fluid from children with cystic fibrosis are associated with high interleukin-8 concentrations., Paul McNally, E Ervine, M D. Shields, Borislav D. Dimitrov, B El Nazir, Clifford C. Taggart, Catherine M. Greene, Noel G. McElvaney, and P Greally

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Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland., Aoife Mullally, Brian J. Cleary, Joe Barry, Tom P. Fahey, and Deirdre J. Murphy

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The Alvarado score for predicting acute appendicitis: a systematic review., Robert Ohle, Fran O'Reilly, Kirsty K. O'Brien, Tom Fahey, and Borislav D. Dimitrov

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Framework for the impact analysis and implementation of Clinical Prediction Rules (CPRs)., Emma Wallace, Susan M. Smith, Rafael Perera-Salazar, Paul Vaucher, Colin McCowan, Gary Collins, Jan Verbakel, Monica Lakhanpaul, Tom Fahey, and International Diagnostic And Prognosis Prediction Group Idapp Group

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Developing an electronic health record (EHR) for methadone treatment recording and decision support., Liang Xiao, Grainne Cousins, Brenda Courtney, Lucy Hederman, Tom Fahey, and Borislav D. Dimitrov

Submissions from 2010

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Service organisation for the secondary prevention of ischaemic heart disease in primary care., Brian S. Buckley, Mary C. Byrne, and Susan M. Smith

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Predicting acute uncomplicated urinary tract infection in women: a systematic review of the diagnostic accuracy of symptoms and signs., Leonie GM Giesen, Grainne Cousins, Borislav D. Dimitrov, Floris A. van de Larr, and Tom Fahey

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Interventions used to improve control of blood pressure in patients with hypertension., Liam G. Glynn, Andrew W. Murphy, Susan M. Smith, Knut Schroeder, and Tom Fahey